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Bone marrow fibrosi...
Bone marrow fibrosis and radiological changes of the long bones in children with acute megakaryocytic leukaemia.
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- Abrahamsson, Jonas, 1954 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics
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- Swolin, Birgitta, 1939 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för laboratoriemedicin, Avdelningen för klinisk kemi/transfusionsmedicin,Institute of Laboratory Medicine, Dept of Clinical Chemistry/Transfusion Medicine
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- Mellander, Lotta, 1941 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics
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(creator_code:org_t)
- 1998
- 1998
- English.
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In: Acta paediatrica (Oslo, Norway : 1992). - 0803-5253. ; 87:10, s. 1093-6
- Related links:
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Abstract
Subject headings
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- The diagnosis of acute megakaryocytic leukaemia (AMkL) may be difficult to establish owing to difficulties in obtaining adequate bone marrow aspirates secondary to bone marrow fibrosis. We describe three children without Down's syndrome under 2 y of age with AMkL. Although none of the patients had the non-random t(1;22) (p13;q13) translocation, bone marrow cells from all patients exhibited chromosome abnormalities with complex karyotypes, including trisomy 21 in two cases. All patients had profound bone marrow fibrosis and characteristic lamellar diaphyseal radiological changes of the long bones.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Keyword
- Bone Marrow
- pathology
- Fatal Outcome
- Female
- Fibrosis
- Humans
- Infant
- Leg Bones
- radiography
- Leukemia
- Megakaryoblastic
- Acute
- microbiology
- Male
Publication and Content Type
- ref (subject category)
- art (subject category)
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