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Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia.
- Saglio, Giuseppe (author)
- Kim, Dong-Wook (author)
- Issaragrisil, Surapol (author)
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- le Coutre, Philipp (author)
- Etienne, Gabriel (author)
- Lobo, Clarisse (author)
- Pasquini, Ricardo (author)
- Clark, Richard E (author)
- Hochhaus, Andreas (author)
- Hughes, Timothy P (author)
- Gallagher, Neil (author)
- Hoenekopp, Albert (author)
- Dong, Mei (author)
- Haque, Ariful (author)
- Larson, Richard A (author)
- Kantarjian, Hagop M (author)
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- (creator_code:org_t)
- 2010
- 2010
- English.
- In: The New England journal of medicine. - 1533-4406. ; 362:24, s. 2251-9
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Nilotinib has been shown to be a more potent inhibitor of BCR-ABL than imatinib. We evaluated the efficacy and safety of nilotinib, as compared with imatinib, in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (CML) in the chronic phase.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- Adolescent
- Adult
- Aged
- Aged
- 80 and over
- Antineoplastic Agents
- administration & dosage
- adverse effects
- therapeutic use
- Benzamides
- Blast Crisis
- prevention & control
- Disease Progression
- Female
- Fusion Proteins
- bcr-abl
- antagonists & inhibitors
- Humans
- Kaplan-Meier Estimate
- Leukemia
- Myeloid
- Chronic-Phase
- drug therapy
- pathology
- Male
- Middle Aged
- Piperazines
- adverse effects
- therapeutic use
- Protein Kinase Inhibitors
- administration & dosage
- adverse effects
- therapeutic use
- Pyrimidines
- administration & dosage
- adverse effects
- therapeutic use
- Young Adult
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- ref (subject category)
- art (subject category)
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- Pasquini, Ricard ...
- Clark, Richard E
- Hochhaus, Andrea ...
- Hughes, Timothy ...
- Gallagher, Neil
- Hoenekopp, Alber ...
- Dong, Mei
- Haque, Ariful
- Larson, Richard ...
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- Wadenvik, Hans, ...
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- MEDICAL AND HEALTH SCIENCES
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- University of Gothenburg
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