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Nitric oxide in the oxygenator sweep gas reduces platelet activation during experimental perfusion.
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- Mellgren, Karin, 1962 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics
- Friberg, L G (author)
- Mellgren, G (author)
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- Wennmalm, A (author)
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- (creator_code:org_t)
- 1996
- 1996
- English.
- In: The Annals of thoracic surgery. - 0003-4975. ; 61:4, s. 1194-8
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Hemorrhage is a major complication experienced in 10% to 35% of neonates treated with extracorporeal life support (ECLS). The increased bleeding tendency is partly due to an ECLS-induced thrombocytopenia and impaired platelet function. In the present study, we evaluated the effect of nitric oxide on the ECLS-induced platelet consumption and activation.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- Analysis of Variance
- Blood Platelets
- chemistry
- drug effects
- Dose-Response Relationship
- Drug
- Extracorporeal Membrane Oxygenation
- instrumentation
- methods
- statistics & numerical data
- Humans
- Nitric Oxide
- administration & dosage
- Plasma
- chemistry
- drug effects
- Platelet Activation
- drug effects
- Time Factors
Publication and Content Type
- ref (subject category)
- art (subject category)
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