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Mass spectrometry-based candidate reference measurement procedure for quantification of amyloid-β in cerebrospinal fluid.
- Leinenbach, Andreas (author)
-
- Pannee, Josef, 1979 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
- Dülffer, Thomas (author)
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- Huber, Andreas (author)
- Bittner, Tobias (author)
- Kobold, Uwe (author)
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- (creator_code:org_t)
- 2014-07-01
- 2014
- English.
- In: Clinical chemistry. - : Oxford University Press (OUP). - 1530-8561 .- 0009-9147. ; 60:7, s. 987-94
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Cerebrospinal fluid (CSF) amyloid-β (Aβ42) is a well-established biomarker for Alzheimer disease. Several immunoassays for Aβ42 exist but differ in absolute concentrations and may suffer from matrix interference, thereby hampering interlaboratory comparisons and the use of general cutoff levels. Together with the IFCC Working Group on CSF Proteins, we developed a candidate reference measurement procedure (RMP) for Aβ42.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Keyword
- Amyloid beta-Peptides
- cerebrospinal fluid
- Biological Markers
- cerebrospinal fluid
- Calibration
- Carbon Isotopes
- Chromatography
- Liquid
- standards
- Humans
- Nitrogen Isotopes
- Peptide Fragments
- cerebrospinal fluid
- Reference Standards
- Tandem Mass Spectrometry
- standards
Publication and Content Type
- ref (subject category)
- art (subject category)
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- University of Gothenburg
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