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Application of the ...
Application of the Gradient Boosted method in randomised clinical trials: Participant variables that contribute to depression treatment efficacy of duloxetine, SSRIs or placebo.
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Dodd, Seetal (author)
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Berk, Michael (author)
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Kelin, Katarina (author)
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Zhang, Qianyi (author)
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- Eriksson, Elias, 1956 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för farmakologi,Institute of Neuroscience and Physiology, Department of Pharmacology
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Deberdt, Walter (author)
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Craig Nelson, J (author)
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(creator_code:org_t)
- Elsevier BV, 2014
- 2014
- English.
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In: Journal of affective disorders. - : Elsevier BV. - 1573-2517 .- 0165-0327. ; 168, s. 284-93
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https://doi.org/10.1...
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Abstract
Subject headings
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- Randomised, placebo-controlled trials of treatments for depression typically collect outcomes data but traditionally only analyse data to demonstrate efficacy and safety. Additional post-hoc statistical techniques may reveal important insights about treatment variables useful when considering inter-individual differences amongst depressed patients. This paper aims to examine the Gradient Boosted Model (GBM), a statistical technique that uses regression tree analyses and can be applied to clinical trial data to identify and measure variables that may influence treatment outcomes.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
Keyword
- depression treatment
- duloxetine
- SSRI
Publication and Content Type
- ref (subject category)
- art (subject category)
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