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Improvement in social function and health-related quality of life after shunt surgery for idiopathic normal-pressure hydrocephalus

Petersen, Jakob (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology
Hellström, Per (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology
Wikkelsö, Carsten, 1947 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology
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Lundgren Nilsson, Åsa, 1965 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology
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 (creator_code:org_t)
Journal of Neurosurgery Publishing Group (JNSPG), 2014
2014
English.
In: Journal of Neurosurgery. - : Journal of Neurosurgery Publishing Group (JNSPG). - 0022-3085 .- 1933-0693. ; 121:4, s. 776-784
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Object. To investigate the impact of shunt surgery on the activity, participation, autonomy, and health-related quality of life (HRQOL) of patients with idiopathic normal-pressure hydrocephalus (iNPH) as well as the effect on caregiver burden. Methods. Thirty-seven patients (median age 70 years, range 50-89 years) with iNPH were evaluated before and 6 months after surgery. Symptoms and signs were assessed by the iNPH scale, activities of daily living (ADL) with the Functional Independence Measure (FIM) and Assessment of Motor and Process Skills (AMPS), autonomy and participation with Impact on Participation and Autonomy (IPA), and caregiver burden with the Caregiver Burden Scale (CBS). HRQOL was evaluated with the EQ-5D (EuroQol Group-5 Dimension health survey). Results. Twenty-four patients (65%) improved clinically (iNPH scale score) and 31(86%) improved their HRQOL after surgery, almost to the same level as found in the normal population. The patients became more independent in physical and cognitive activities, and participation and autonomy improved. The caregiver burden was decreased among caregivers to male patients but remained unchanged on the overall group level. Conclusions. After shunt surgery, patients with iNPH showed improvement in most aspects of social life, they became more independent, and their quality of life returned to nearly normal.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Keyword

idiopathic normal pressure hydrocephalus
quality of life
activity
participation
autonomy
caregiver
EUROPEAN MULTICENTER
POPULATION
INPH
NEUROPSYCHOLOGY
PREVALENCE
BURDEN
SCALE
Clinical Neurology
Surgery

Publication and Content Type

ref (subject category)
art (subject category)

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Petersen, Jakob
Hellström, Per
Wikkelsö, Carste ...
Lundgren Nilsson ...
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MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
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University of Gothenburg

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