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Validation and comp...
Validation and comparison of three formulae to estimate sodium and potassium excretion from a single morning fasting urine compared to 24-h measures in 11 countries
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Mente, A. (author)
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O'Donnell, M. J. (author)
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Dagenais, G. (author)
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Wielgosz, A. (author)
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Lear, S. A. (author)
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McQueen, M. J. (author)
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Jiang, Y. (author)
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Xingyu, W. (author)
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Jian, B. (author)
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Calik, K. B. (author)
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Akalin, A. A. (author)
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Mony, P. (author)
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Devanath, A. (author)
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Yusufali, A. H. (author)
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Lopez-Jaramillo, P. (author)
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Avezum, A., Jr. (author)
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Yusoff, K. (author)
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- Rosengren, Annika, 1951 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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Kruger, L. (author)
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Orlandini, A. (author)
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Rangarajan, S. (author)
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Teo, K. (author)
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Yusuf, S. (author)
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(creator_code:org_t)
- 2014
- 2014
- English.
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In: Journal of Hypertension. - 0263-6352. ; 32:5, s. 1005-15
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https://doi.org/10.1...
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Abstract
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- BACKGROUND AND OBJECTIVES: Although 24-h urinary measure to estimate sodium and potassium excretion is the gold standard, it is not practical for large studies. We compared estimates of 24-h sodium and potassium excretion from a single morning fasting urine (MFU) using three different formulae in healthy individuals. METHODS: We studied 1083 individuals aged 35-70 years from the general population in 11 countries. A 24-h urine and MFU specimen were obtained from each individual. A subset of 448 individuals repeated the measures after 30-90 days. The Kawasaki, Tanaka, and INTERSALT formulae were used to estimate urinary excretion from a MFU specimen. RESULTS: The intraclass correlation coefficient (ICC) between estimated and measured sodium excretion was higher with Kawasaki (0.71; 95% confidence interval, CI: 0.65-0.76) compared with INTERSALT (0.49; 95% CI: 0.29-0.62) and Tanaka (0.54; 95% CI: 0.42-0.62) formulae (P <0.001). For potassium, the ICC was higher with the Kawasaki (0.55; 95% CI: 0.31-0.69) than the Tanaka (0.36; 95% CI: -0.07 to 0.60; P <0.05) formula (no INTERSALT formula exists for potassium). The degree of bias (vs. the 24-h urine) for sodium was smaller with Kawasaki (+313 mg/day; 95% CI: +182 to +444) compared with INTERSALT (-872 mg/day; 95% CI: -728 to -1016) and Tanaka (-548 mg/day; 95% CI: -408 to -688) formulae (P <0.001 and P = 0.02, respectively). Similarly for potassium, the Kawasaki formula provided the best agreement and least bias. Blood pressure correlated most closely and similarly with the 24-h and Kawasaki estimates for sodium compared with the other two formulae. CONCLUSION: In a diverse population, the Kawasaki formula is the most valid and least biased method of estimating 24-h sodium excretion from a single MFU and is suitable for population studies.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
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- ref (subject category)
- art (subject category)
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- By the author/editor
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Mente, A.
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O'Donnell, M. J.
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Dagenais, G.
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Wielgosz, A.
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Lear, S. A.
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McQueen, M. J.
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show more...
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Jiang, Y.
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Xingyu, W.
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Jian, B.
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Calik, K. B.
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Akalin, A. A.
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Mony, P.
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Devanath, A.
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Yusufali, A. H.
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Lopez-Jaramillo, ...
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Avezum, A., Jr.
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Yusoff, K.
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Rosengren, Annik ...
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Kruger, L.
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Orlandini, A.
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Rangarajan, S.
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Teo, K.
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Yusuf, S.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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Journal of Hyper ...
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University of Gothenburg