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No evidence of pig ...
No evidence of pig DNA or retroviral infection in patients with short-term extracorporeal connection to pig kidneys.
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Patience, C (author)
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Patton, G S (author)
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Takeuchi, Y (author)
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Weiss, R A (author)
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McClure, M O (author)
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- Rydberg, Lennart, 1944 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för laboratoriemedicin, Avdelningen för klinisk kemi/transfusionsmedicin,Institute of Laboratory Medicine, Dept of Clinical Chemistry/Transfusion Medicine
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- Breimer, Michael, 1951 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för kirurgi,Institute of Surgical Sciences, Department of Surgery
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(creator_code:org_t)
- 1998
- 1998
- English.
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In: Lancet. - 0140-6736. ; 352:9129, s. 699-701
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Subject headings
Close
- The xenotransplantation of organs and tissues, in particular those from pigs, is viewed as a means to alleviate the shortage of human donor organs and cells available for transplantation and also as a therapy for other diseases. The potential microbiological hazards of xenotransplantation have recently attracted much attention. One concern is over pig endogenous retroviruses (PERV). Until the possible consequences of infection by PERV are better understood it is unlikely that a significant number of porcine xenotransplants will proceed. However, a small number of patients have already been treated with or exposed to living porcine cells or tissue, and investigation of these patients may provide valuable information.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Keyword
- Adult
- Animals
- Chronic Disease
- DNA
- analysis
- Extracorporeal Circulation
- Genome
- Viral
- Glomerulonephritis
- therapy
- Humans
- Male
- Middle Aged
- Renal Dialysis
- Retroviridae
- genetics
- isolation & purification
- Retroviridae Infections
- transmission
- Swine
- Time Factors
- Viral Envelope Proteins
Publication and Content Type
- ref (subject category)
- art (subject category)
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