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Genotoxic effects o...
Genotoxic effects of CdS quantum dots and Ag2S nanoparticles in fish cell lines (RTG-2)
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Munari, M. (author)
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- Sturve, Joachim, 1966 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biologi och miljövetenskap,Department of Biological and Environmental Sciences
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Frenzilli, G. (author)
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Sanders, M. B. (author)
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Brunelli, A. (author)
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Marcomini, A. (author)
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Nigro, M. (author)
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Lyons, B. P. (author)
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(creator_code:org_t)
- Elsevier BV, 2014
- 2014
- English.
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In: Mutation Research-Genetic Toxicology and Environmental Mutagenesis. - : Elsevier BV. - 1383-5718. ; 775-776, s. 89-93
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https://doi.org/10.1...
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Abstract
Subject headings
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- The increasing use of nanotechnologies will lead to significant releases of engineered nanoparticles into the aquatic environment, where their impact is still poorly characterized. In the present paper, the genotoxic and cytotoxic properties of CdS quantum dots (QDs) and silver sulphide (Ag2S) coated with methyl polyethylene glycol (M-PEG) were investigated in a rainbow trout cell line (RTG-2). The results showed that CdS QDs were highly cytotoxic at high concentrations (10 and 50 mu g/ml), and exhibited a concentration-dependent genotoxicity in the sub-toxic range (0.01-1 mu g/ml) after 24h exposure. Ag2S showed neither genotoxic nor cytotoxic effects. (C) 2014 Elsevier B.V. All rights reserved.
Subject headings
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
Keyword
- DNA damage
- Fish cell culture
- Nanoparticles
- Quantum dots
- Silver
- Cadmium
- IN-VITRO
- SILVER NANOPARTICLES
- COMET ASSAY
- RAINBOW-TROUT
- DNA-DAMAGE
- MYTILUS-GALLOPROVINCIALIS
- OXIDATIVE STRESS
- IMMUNE-SYSTEM
- LIVE CELLS
- TOXICITY
- Biotechnology & Applied Microbiology
- Genetics & Heredity
- Toxicology
Publication and Content Type
- ref (subject category)
- art (subject category)
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