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Minimal experimenta...
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Lötvall, Jan,1956Gothenburg University,Göteborgs universitet,Krefting Research Centre
(author)
Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles.
- Article/chapterEnglish2014
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LIBRIS-ID:oai:gup.ub.gu.se/215044
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https://gup.ub.gu.se/publication/215044URI
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https://doi.org/10.3402/jev.v3.26913DOI
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Subject category:vet swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Secreted membrane-enclosed vesicles, collectively called extracellular vesicles (EVs), which include exosomes, ectosomes, microvesicles, microparticles, apoptotic bodies and other EV subsets, encompass a very rapidly growing scientific field in biology and medicine. Importantly, it is currently technically challenging to obtain a totally pure EV fraction free from non-vesicular components for functional studies, and therefore there is a need to establish guidelines for analyses of these vesicles and reporting of scientific studies on EV biology. Here, the International Society for Extracellular Vesicles (ISEV) provides researchers with a minimal set of biochemical, biophysical and functional standards that should be used to attribute any specific biological cargo or functions to EVs.
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Hill, Andrew F
(author)
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Hochberg, Fred
(author)
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Buzás, Edit I
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Di Vizio, Dolores
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Gardiner, Christopher
(author)
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Gho, Yong Song,1964
(author)
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Kurochkin, Igor V
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Mathivanan, Suresh
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Quesenberry, Peter
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Sahoo, Susmita
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Tahara, Hidetoshi
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Wauben, Marca H
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Witwer, Kenneth W
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Théry, Clotilde
(author)
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Göteborgs universitetKrefting Research Centre
(creator_code:org_t)
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In:Journal of extracellular vesicles: Wiley32001-3078
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Lötvall, Jan, 19 ...
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Hill, Andrew F
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Hochberg, Fred
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Buzás, Edit I
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Di Vizio, Dolore ...
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Gardiner, Christ ...
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Gho, Yong Song, ...
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Mathivanan, Sure ...
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Sahoo, Susmita
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Tahara, Hidetosh ...
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Wauben, Marca H
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Witwer, Kenneth ...
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Théry, Clotilde
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University of Gothenburg