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Dynamics and Stabil...
Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life
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- Bäckhed, Fredrik, 1973 (author)
- Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory,The Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden & Novo Nordisk Foundation Center for Basic Metabolic Research, Section for Metabolic Receptology and Enteroendocrinology, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
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- Roswall, Josefine (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,Department of Pediatrics, Hallands Hospital Halmstad, Halmstad, Sweden & Göteborg Paediatric Growth Research Center, Department of Paediatrics, the University of Gothenburg, Queen Silvia Children’s Hospital, Gothenburg, Sweden
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- Peng, Y. Q. (author)
- BGI-Shenzhen, Shenzhen, China &Department of Biology, University of Copenhagen, Copenhagen, Denmark
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Feng, Qing-Ping (author)
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- Jia, H. J. (author)
- BGI-Shenzhen, Shenzhen, China
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- Kovatcheva-Datchary, Petia (author)
- Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory,The Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden
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Liu, Y (author)
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- Xia, Y. (author)
- BGI-Shenzhen, Shenzhen, China
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- Xie, H. L. (author)
- BGI-Shenzhen, Shenzhen, China
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- Zhong, H. Z. (author)
- BGI-Shenzhen, Shenzhen, China
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- Khan, Muhammad Tanweer (author)
- Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory,The Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden
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- Zhang, J. F. (author)
- BGI-Shenzhen, Shenzhen, China
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- Li, J. H. (author)
- BGI-Shenzhen, Shenzhen, China
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- Xiao, L. (author)
- BGI-Shenzhen, Shenzhen, China
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- Al-Aama, J. (author)
- BGI-Shenzhen, Shenzhen, China & Princess Al Jawhara Albrahim Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Saudi Arabia
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- Zhang, D. Y. (author)
- BGI-Shenzhen, Shenzhen, China
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- Lee, Ying Shiuan (author)
- Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory,The Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden
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- Kotowska, D. (author)
- Department of Biology, University of Copenhagen, Copenhagen, Denmark
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- Colding, C. (author)
- Department of Biology, University of Copenhagen, Copenhagen, Denmark
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- Tremaroli, Valentina, 1978 (author)
- Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory,The Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden
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- Yin, Y. (author)
- BGI-Shenzhen, Shenzhen, China
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- Bergman, Stefan (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,Göteborg Paediatric Growth Research Center, Department of Paediatrics, the University of Gothenburg, Queen Silvia Children’s Hospital, Gothenburg & Research and Development Center Spenshult, Oskarström, Sweden
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- Xu, X. (author)
- BGI-Shenzhen, Shenzhen, China
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- Madsen, L. (author)
- Department of Biology, University of Copenhagen, Copenhagen, Denmark & National Institute of Nutrition and Seafood Research, Bergen, Norway
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- Kristiansen, K. (author)
- BGI-Shenzhen, Shenzhen, China & Department of Biology, University of Copenhagen, Copenhagen, Denmark
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- Dahlgren, Jovanna, 1964 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,Göteborg Paediatric Growth Research Center, Department of Paediatrics, the University of Gothenburg, Queen Silvia Children’s Hospital, Gothenburg &
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- Jun, W. (author)
- BGI-Shenzhen, Shenzhen, China, Department of Biology, University of Copenhagen, Copenhagen, Denmark, Princess Al Jawhara Albrahim Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Saudi Arabia, Macau University of Science and Technology, Avenida Wai long, Taipa, China & Department of Medicine and State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong
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(creator_code:org_t)
- Cambridge : Elsevier BV, 2015
- 2015
- English.
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In: Cell Host & Microbe. - Cambridge : Elsevier BV. - 1931-3128 .- 1934-6069. ; 17:5, s. 690-703
- Related links:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
Close
- The gut microbiota is central to human health, but its establishment in early life has not been quantitatively and functionally examined. Applying metagenomic analysis on fecal samples from a large cohort of Swedish infants and their mothers, we characterized the gut microbiome during the first year of life and assessed the impact of mode of delivery and feeding on its establishment. In contrast to vaginally delivered infants, the gut microbiota of infants delivered by C-section showed significantly less resemblance to their mothers. Nutrition had a major impact on early microbiota composition and function, with cessation of breast-feeding, rather than introduction of solid food, being required for maturation into an adult-like microbiota. Microbiota composition and ecological network had distinctive features at each sampled stage, in accordance with functional maturation of the microbiome. Our findings establish a framework for understanding the interplay between the gut microbiome and the human body in early life.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Keyword
- INTESTINAL MICROBIOTA
- INFANT GUT
- METAGENOME
- BACTERIA
- MELATONIN
- PROTEINS
- CHILDREN
- NEWBORNS
- CATALOG
- DISEASE
- Microbiology
- Parasitology
- Virology
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Bäckhed, Fredrik ...
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Roswall, Josefin ...
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Peng, Y. Q.
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Feng, Qing-Ping
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Jia, H. J.
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Kovatcheva-Datch ...
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show more...
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Liu, Y
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Xia, Y.
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Xie, H. L.
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Zhong, H. Z.
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Khan, Muhammad T ...
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Zhang, J. F.
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Li, J. H.
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Xiao, L.
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Al-Aama, J.
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Zhang, D. Y.
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Lee, Ying Shiuan
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Kotowska, D.
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Colding, C.
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Tremaroli, Valen ...
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Yin, Y.
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Bergman, Stefan
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Xu, X.
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Madsen, L.
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Kristiansen, K.
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Dahlgren, Jovann ...
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Jun, W.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Pediatrics
- Articles in the publication
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Cell Host & Micr ...
- By the university
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University of Gothenburg
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Halmstad University