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- Jack, C. R. (author)
Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2
- Article/chapterEnglish2015
Publisher, publication year, extent ...
- 2015-07
- Wiley,2015
Numbers
- LIBRIS-ID:oai:gup.ub.gu.se/220679
- https://gup.ub.gu.se/publication/220679URI
- https://doi.org/10.1016/j.jalz.2015.05.002DOI
Supplementary language notes
- Language:English
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- SwePubSwePub
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Notes
- Introduction: Alzheimer's Disease Neuroimaging Initiative (ADNI) is now in its 10th year. The primary objective of the magnetic resonance imaging (MRI) core of ADNI has been to improve methods for clinical trials in Alzheimer's disease (AD) and related disorders. Methods: We review the contributions of the MRI core from present and past cycles of ADNI (ADNI-1, -Grand Opportunity and -2). We also review plans for the future-ADNI-3. Results: Contributions of the MRI core include creating standardized acquisition protocols and quality control methods; examining the effect of technical features of image acquisition and analysis on outcome metrics; deriving sample size estimates for future trials based on those outcomes; and piloting the potential utility of MR perfusion, diffusion, and functional connectivity measures in multicenter clinical trials. Discussion: Over the past decade the MRI core of ADNI has fulfilled its mandate of improving methods for clinical trials in AD and will continue to do so in the future. (C) 2015 The Authors. Published by Elsevier Inc. on behalf of the Alzheimer's Association.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Neurologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Neurology hsv//eng
- Alzheimer's disease
- Alzheimer's Disease Neuroimaging Initiative
- ADNI
- Diffusion
- MRI
- MILD COGNITIVE IMPAIRMENT
- TENSOR-BASED MORPHOMETRY
- PREDICT BRAIN
- ATROPHY
- CSF BIOMARKERS
- AMYLOID-BETA
- NATIONAL INSTITUTE
- ASSOCIATION
- WORKGROUPS
- DIAGNOSTIC GUIDELINES
- CLINICAL-TRIALS
- NEURODEGENERATIVE
- DISEASE
- Clinical Neurology
Added entries (persons, corporate bodies, meetings, titles ...)
- Barnes, J. (author)
- Bernstein, M. A. (author)
- Borowski, B. J. (author)
- Brewer, J. (author)
- Clegg, S. (author)
- Dale, A. M. (author)
- Carmichael, O. (author)
- Ching, C. (author)
- DeCarli, C. (author)
- Desikan, R. S. (author)
- Fennema-Notestine, C. (author)
- Fjell, A. M. (author)
- Fletcher, E. (author)
- Fox, N. C. (author)
- Gunter, J. (author)
- Gutman, B. A. (author)
- Holland, D. (author)
- Hua, X. (author)
- Insel, P. (author)
- Kantarci, K. (author)
- Killiany, R. J. (author)
- Krueger, G. (author)
- Leung, K. K. (author)
- Mackin, S. (author)
- Maillard, P. (author)
- Malone, I. B. (author)
- Mattsson, Niklas,1979Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology(Swepub:gu)xmattn (author)
- McEvoy, L. (author)
- Modat, M. (author)
- Mueller, S. (author)
- Nosheny, R. (author)
- Ourselin, S. (author)
- Schuff, N. (author)
- Senjem, M. L. (author)
- Simonson, A. (author)
- Thompson, P. M. (author)
- Rettmann, D. (author)
- Vemuri, P. (author)
- Walhovd, K. (author)
- Zhao, Y. S. (author)
- Zuk, S. (author)
- Weiner, M. (author)
- Göteborgs universitetInstitutionen för neurovetenskap och fysiologi (creator_code:org_t)
Related titles
- In:Alzheimers & Dementia: Wiley11:7, s. 740-7561552-52601552-5279
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- Dale, A. M.
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