Search: onr:"swepub:oai:gup.ub.gu.se/224029" > A population-based ...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 05751naa a2200733 4500 | |
001 | oai:gup.ub.gu.se/224029 | |
003 | SwePub | |
008 | 240910s2015 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:uu-264667 | |
009 | oai:DiVA.org:umu-109914 | |
024 | 7 | a https://gup.ub.gu.se/publication/2240292 URI |
024 | 7 | a https://doi.org/10.1111/pai.124222 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2646672 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1099142 URI |
040 | a (SwePub)gud (SwePub)uud (SwePub)umu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Bjerg, Anders,d 1982u Umeå universitet,Gothenburg University,Göteborgs universitet,Krefting Research Centre,Univ Gothenburg, Krefting Res Ctr, Dept Internal Med & Clin Nutr, SE-40530 Gothenburg, Sweden.;Umea Univ, Dept Publ Hlth & Clin Med, OLIN Unit, Occupat & Environm,Med, Umea, Sweden.,Yrkes- och miljömedicin,Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Göteborg, Sweden4 aut0 (Swepub:umu)ansbjd01 |
245 | 1 0 | a A population-based study of animal component sensitization, asthma, and rhinitis in schoolchildren |
264 | c 2015-07-30 | |
264 | 1 | b Wiley,c 2015 |
520 | a BackgroundAnimal sensitization is a major determinant of asthma in children. Component-resolved studies of unselected pediatric populations are lacking. The aim was to describe sensitization to animal components and the association with asthma and rhinitis in animal-sensitized schoolchildren. MethodsA random sample of 696 children (11-12years) from a Swedish population-based cohort was tested for sensitization to cat, dog, and horse dander using ImmunoCAP. Sera from animal-sensitized children were further analyzed by microarray including three allergen components from cat, four from dog, and two from horse. The parents completed an expanded ISAAC questionnaire. ResultsOf 259 animal-sensitized children (0.1 kU(A)/l), 51% were sensitized to all three, 23% to two, and 25% to one species. Current asthma and asthma symptoms following contact with cats were associated with co-sensitization to Fel d 1 and Fel d 4. This association was seen already at moderate-level sensitization (1-15 ISU) to Fel d 4, at which level most children were sensitized to Fel d 1, as well. In dog-sensitized children, the majority was sensitized to more than one dog component, and co-sensitization to Can f 5 and Can f 1/f 2 conferred the greatest risk for asthma. Sensitization to the highly cross-reactive serum albumins was uncommon and not associated with asthma. ConclusionsAmong schoolchildren in northern Sweden, where mite allergy is uncommon, furry animals were the primary perennial sensitizers. Asthma was associated with higher levels of component sensitization, and sensitization to more than one component from the same animal conferred the greatest risk. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng |
653 | a children | |
653 | a allergy | |
653 | a furry animals | |
653 | a allergen components | |
653 | a component-resolved diagnosis | |
653 | a asthma | |
653 | a rhinitis | |
653 | a obstructive lung-disease | |
653 | a severe childhood asthma | |
653 | a northern sweden | |
653 | a allergic sensitization | |
653 | a ige sensitization | |
653 | a risk-factors | |
653 | a time trends | |
653 | a children | |
653 | a food | |
653 | a cat | |
653 | a Allergy | |
653 | a Immunology | |
653 | a Pediatrics | |
653 | a children | |
700 | 1 | a Winberg, Annau Umeå universitet,Pediatrik4 aut0 (Swepub:umu)anwi0077 |
700 | 1 | a Berthold, M.u ThermoFisher Sci, Uppsala, Sweden.4 aut |
700 | 1 | a Mattsson, L.u ThermoFisher Sci, Uppsala, Sweden.4 aut |
700 | 1 | a Borres, Magnus P.u Uppsala universitet,Pediatrik,ThermoFisher Sci, Uppsala, Sweden.4 aut0 (Swepub:uu)magbo385 |
700 | 1 | a Rönmark, Eva,d 1953u Umeå universitet,Gothenburg University,Göteborgs universitet,Krefting Research Centre,Univ Gothenburg, Krefting Res Ctr, Dept Internal Med & Clin Nutr, SE-40530 Gothenburg, Sweden.;Umea Univ, Dept Publ Hlth & Clin Med, OLIN Unit, Occupat & Environm,Med, Umea, Sweden.,Yrkes- och miljömedicin,Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Göteborg, Sweden4 aut0 (Swepub:umu)evra0004 |
710 | 2 | a Göteborgs universitetb Krefting Research Centre4 org |
773 | 0 | t Pediatric Allergy and Immunologyd : Wileyg 26:6, s. 557-563q 26:6<557-563x 0905-6157x 1399-3038 |
856 | 4 8 | u https://gup.ub.gu.se/publication/224029 |
856 | 4 8 | u https://doi.org/10.1111/pai.12422 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-264667 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-109914 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
Copy and save the link in order to return to this view