Role of noroviruses as aetiological agents of diarrhoea in developing countries

• Diarrhoea is considered to be the second leading cause of death due to infections among children <5 years of age worldwide that may be caused by bacteria, parasites, viruses and non-infectious agents. The major causative agents of diarrhoea in developing countries may vary from those in developed countries. Noroviruses are considered to be the most common cause of acute diarrhoea in both children and adults in industrialized countries. On the other hand, there is a lack of comprehensive epidemiological evidence from developing countries that norovirus is a major cause of diarrhoea. In these regions, asymptomatic norovirus infections are very common, and similar detection rates have been observed in patients with diarrhoea and asymptomatic persons. This review summarizes the current knowledge of norovirus infection in developing countries and seeks to position infections with noroviruses among those of other enteropathogens in terms of disease burden in these regions.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Infektionsmedicin (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Infectious Medicine (hsv//eng)

Keyword

blood group antigens

norwalk-like viruses

infectious nonbacterial

gastroenteritis

winter vomiting disease

treated waste-water

linked-immunosorbent-assay

acute childhood diarrhea

round structured

virus

human enteric viruses

united-states

Biotechnology & Applied Microbiology

Virology

Publication and Content Type

ref (subject category)

art (subject category)