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Bioceramic Implant ...
Bioceramic Implant Induces Bone Healing of Cranial Defects.
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- Engstrand, Thomas (author)
- Karolinska Institutet
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- Kihlström, Lars (author)
- Karolinska Institutet
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- Lundgren, Kalle (author)
- Karolinska Institutet
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- Trobos, Margarita, 1980 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials,Univ Gothenburg, Sahlgrenska Acad, Inst Clin Sci, Dept Biomat, Gothenburg, Sweden.;Univ Gothenburg, Vinn Excellence Ctr Biomat & Cell Therapy, Biomatcell, Gothenburg, Sweden.
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- Engqvist, Håkan (author)
- Uppsala universitet,Tillämpad materialvetenskap
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- Thomsen, Peter, 1953 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials,Univ Gothenburg, Sahlgrenska Acad, Inst Clin Sci, Dept Biomat, Gothenburg, Sweden.;Univ Gothenburg, Vinn Excellence Ctr Biomat & Cell Therapy, Biomatcell, Gothenburg, Sweden.
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(creator_code:org_t)
- LIPPINCOTT WILLIAMS & WILKINS, 2015
- 2015
- English.
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In: Plastic and reconstructive surgery. Global open. - : LIPPINCOTT WILLIAMS & WILKINS. - 2169-7574. ; 3:8
- Related links:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- Autologous bone or inert alloplastic materials used in cranial reconstructions are techniques that are associated with resorption, infection, and implant exposure. As an alternative, a calcium phosphate-based implant was developed and previously shown to potentially stimulate bone growth. We here uncover evidence of induced bone formation in 2 patients. Histological examination 9 months postoperatively showed multinuclear cells in the central defect zone and bone ingrowth in the bone-implant border zone. An increased expression of bone-associated markers was detected. The other patient was investigated 50 months postoperatively. Histological examination revealed ceramic materials covered by vascularized compact bone. The bone regenerative effect induced by the implant may potentially improve long-term clinical outcome compared with conventional techniques, which needs to be verified in a clinical study.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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