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  • Timberg, PontusLund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Malmö,Lund University Research Groups (author)

Potential for lower absorbed dose in digital mammography: A JAFROC experiment using clinical hybrid images with simulated dose reduction

  • Article/chapterEnglish2006

Publisher, publication year, extent ...

  • SPIE,2006

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/235497
  • https://gup.ub.gu.se/publication/235497URI
  • https://doi.org/10.1117/12.653419DOI
  • https://lup.lub.lu.se/record/1405947URI

Supplementary language notes

  • Language:English

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  • Subject category:vet swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • To determine how image quality linked to tumor detection is affected by reducing the absorbed dose to 50% and 30% of the clinical levels represented by an average glandular dose (AGO) level of 1.3 mGy for a standard breast according to European guidelines. Materials and methods: 90 normal, unprocessed images were acquired from the screening department using a full-field digital mammography (FFDM) unit Mammomat Novation (Siemens). Into 40 of these, one to three simulated tumors were inserted per image at various positions. These tumors represented irregular-shaped malignant masses. Dose reduction was simulated in all 90 images by adding simulated quantum noise to represent images acquired at 50% and 30% of the original dose, resulting in 270 images, which were subsequently processed for final display. Four radiologists participated in a free-response receiver operating characteristics (FROG) study in which they searched for and marked suspicious positions of the masses as well as rated their degree of suspicion of occurrence on a one to four scale. Using the jackknife FROG (JAFROC) method, a score between 0 and 1 (where 1 represents best performance), referred to as a figure-of-merit (FOM), was calculated for each dose level. Results: The FOM was 0.73, 0.70, and 0.68 for the 100%, 50% and 30% dose levels, respectively. Using Analysis of the Variance (ANOVA) to test for statistically significant differences between any two of the three FOMs revealed that they were not statistically distinguishable (p-value of 0.26). Conclusion: For the masses used in this experiment, there was no significant change in detection by increasing quantum noise, thus indicating a potential for dose reduction.

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  • Ruschin, MarkLund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Malmö,Lund University Research Groups(Swepub:lu)rfa-mru (author)
  • Båth, Magnus,1974Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiofysik,Institute of Clinical Sciences, Department of Radiation Physics(Swepub:gu)xbatma (author)
  • Hemdal, BengtLund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Malmö,Lund University Research Groups(Swepub:lu)rfa-bhe (author)
  • Andersson, IngvarLund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine(Swepub:lu)ront-ian (author)
  • Mattsson, SörenLund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Malmö,Lund University Research Groups(Swepub:lu)rfa-sma (author)
  • Chakraborty, D. (author)
  • Saunders, R. (author)
  • Samei, E. (author)
  • Tingberg, AndersLund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Malmö,Lund University Research Groups(Swepub:lu)rfa-ati (author)
  • Medicinsk strålningsfysik, MalmöForskargrupper vid Lunds universitet (creator_code:org_t)

Related titles

  • In:Progress in Biomedical Optics and Imaging - Proceedings of SPIE: SPIE6146, s. 14614-146141605-7422
  • In:Medical Imaging 2006: Image Perception, Observer Performance and Technology Assessment: SPIE6146, s. 14614-146140277-786X1996-756X

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