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Prognostic signific...
Prognostic significance of pulsatile tinnitus in cervical artery dissection
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Kellert, L. (author)
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Kloss, M. (author)
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Pezzini, A. (author)
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Debette, S. (author)
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Leys, D. (author)
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Caso, V. (author)
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Thijs, V. N. (author)
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Bersano, A. (author)
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Touze, E. (author)
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- Tatlisumak, Turgut (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology
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Traenka, C. (author)
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Lyrer, P. A. (author)
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Engelter, S. T. (author)
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Metso, T. M. (author)
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Grond-Ginsbach, C. (author)
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(creator_code:org_t)
- 2016-04-27
- 2016
- English.
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In: European Journal of Neurology. - : Wiley. - 1351-5101. ; 23:7, s. 1183-1187
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Abstract
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- Background and purposeOur aim was to investigate whether pulsatile tinnitus (PT) in cervical artery dissection (CeAD) has prognostic significance. MethodsAll CeAD patients from the CADISP (Cervical Artery Dissection and Ischemic Stroke Patients) study with documentation of PT were analysed. The presence of PT was systematically assessed using a standardized questionnaire. Stroke severity at admission was defined according to the National Institutes of Health Stroke Scale (NIHSS). Excellent outcome after 3 months was defined as a modified Rankin Scale of 0-1. ResultsSixty-three of 778 patients (8.1%) reported PT. PT+ patients presented less often with ischaemic stroke (41.3% vs. 63.9%, P < 0.001), more often with dissection in the internal carotid artery (85.7% vs. 64.2%, P = 0.001), less often with vessel occlusion (19.0% vs. 34.1%, P = 0.017) and more often with excellent outcome at 3 months (92.1% vs. 75.4%, P = 0.002). Logistic regression analysis identified PT as an independent predictor of excellent outcome after 3 months [odds ratio (OR) 3.96, 95% confidence interval (CI) 1.22-12.87] adjusted to significant outcome predictors NIHSS on admission (OR 0.82, 95% CI 0.79-0.86), Horner syndrome (OR 1.95, 95% CI 1.16-3.29) and vessel occlusion (OR 0.62, 95% CI 0.40-0.94) and to non-significant predictors age, sex, pain and location of CeAD. ConclusionThe presence of PT in CeAD is associated with a benign clinical course and predicts a favourable outcome.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- acute ischaemic stroke
- cervical artery dissection
- outcome
- pulsatile tinnitus
- risk-factors
- diagnosis
- gender
- Neurosciences & Neurology
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Kellert, L.
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Kloss, M.
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Pezzini, A.
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Debette, S.
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Leys, D.
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Caso, V.
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show more...
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Thijs, V. N.
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Bersano, A.
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Touze, E.
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Tatlisumak, Turg ...
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Traenka, C.
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Lyrer, P. A.
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Engelter, S. T.
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Metso, T. M.
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Grond-Ginsbach, ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
- Articles in the publication
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European Journal ...
- By the university
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University of Gothenburg