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A Placebo-Controlle...
A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.
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Nevens, Frederik (author)
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Andreone, Pietro (author)
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Mazzella, Giuseppe (author)
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Strasser, Simone I (author)
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Bowlus, Christopher (author)
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Invernizzi, Pietro (author)
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Drenth, Joost P H (author)
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Pockros, Paul J (author)
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Regula, Jaroslaw (author)
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Beuers, Ulrich (author)
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Trauner, Michael (author)
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Jones, David E (author)
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Floreani, Annarosa (author)
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Hohenester, Simon (author)
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Luketic, Velimir (author)
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Shiffman, Mitchell (author)
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van Erpecum, Karel J (author)
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Vargas, Victor (author)
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Vincent, Catherine (author)
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Hirschfield, Gideon M (author)
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Shah, Hemant (author)
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Hansen, Bettina (author)
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Lindor, Keith D (author)
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- Marschall, Hanns-Ulrich, 1954 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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Kowdley, Kris V (author)
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Hooshmand-Rad, Roya (author)
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Marmon, Tonya (author)
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Sheeron, Shawn (author)
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Pencek, Richard (author)
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MacConell, Leigh (author)
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Pruzanski, Mark (author)
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Shapiro, David (author)
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(creator_code:org_t)
- 2016
- 2016
- English.
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In: The New England journal of medicine. - 1533-4406. ; 375:7, s. 631-43
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https://doi.org/10.1...
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Abstract
Subject headings
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- Primary biliary cholangitis (formerly called primary biliary cirrhosis) can progress to cirrhosis and death despite ursodiol therapy. Alkaline phosphatase and bilirubin levels correlate with the risk of liver transplantation or death. Obeticholic acid, a farnesoid X receptor agonist, has shown potential benefit in patients with this disease.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Keyword
- Adult
- Aged
- Alkaline Phosphatase
- blood
- Bile Acids and Salts
- blood
- Bone Density
- drug effects
- Chenodeoxycholic Acid
- adverse effects
- analogs & derivatives
- therapeutic use
- Double-Blind Method
- Female
- Fibroblast Growth Factors
- blood
- Humans
- Liver Cirrhosis
- etiology
- Liver Cirrhosis
- Biliary
- blood
- complications
- drug therapy
- Male
- Middle Aged
- Pruritus
- chemically induced
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Nevens, Frederik
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Andreone, Pietro
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Mazzella, Giusep ...
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Strasser, Simone ...
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Bowlus, Christop ...
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Invernizzi, Piet ...
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show more...
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Drenth, Joost P ...
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Pockros, Paul J
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Regula, Jaroslaw
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Beuers, Ulrich
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Trauner, Michael
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Jones, David E
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Floreani, Annaro ...
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Hohenester, Simo ...
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Luketic, Velimir
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Shiffman, Mitche ...
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van Erpecum, Kar ...
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Vargas, Victor
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Vincent, Catheri ...
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Hirschfield, Gid ...
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Shah, Hemant
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Hansen, Bettina
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Lindor, Keith D
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Marschall, Hanns ...
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Kowdley, Kris V
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Hooshmand-Rad, R ...
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Marmon, Tonya
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Sheeron, Shawn
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Pencek, Richard
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MacConell, Leigh
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Pruzanski, Mark
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Shapiro, David
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Gastroenterology ...
- Articles in the publication
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The New England ...
- By the university
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University of Gothenburg