Casein Kinase 2 - A Kinase that Inhibits Brown Fat Formation

• In adipose tissue, there is a delicate balance between storing and expending energy. In this issue, Shinoda et al. (2015) use phosphoproteomics to identify casein kinase 2 (CK2) as a suppressor of brown adipocyte formation, providing insights into how adipose tissue regulates its composition of white versus brown adipocytes. © 2015 Elsevier Inc.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinsk bioteknologi -- Biomaterialvetenskap (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Medical Biotechnology -- Biomaterials Science (hsv//eng)

NATURVETENSKAP  -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)

NATURAL SCIENCES  -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)

Keyword

Article; brown adipocyte; brown adipose tissue; cell differentiation; cell line; cell proliferation; enzyme activation; enzyme activity; enzyme inhibition; human; lipid composition; non insulin dependent diabetes mellitus; nonhuman; obesity; priority journal; protein phosphorylation; proteomics; regulatory mechanism; white adipocyte; adipocyte; brown adipose tissue; energy metabolism; metabolism

Publication and Content Type

ref (subject category)

art (subject category)