Search: onr:"swepub:oai:gup.ub.gu.se/244286" > Low aerobic capacit...
Fältnamn | Indikatorer | Metadata |
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000 | 05949naa a2200601 4500 | |
001 | oai:gup.ub.gu.se/244286 | |
003 | SwePub | |
008 | 240528s2016 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:uu-305545 | |
024 | 7 | a https://gup.ub.gu.se/publication/2442862 URI |
024 | 7 | a https://doi.org/10.1177/20474873166554662 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3055452 URI |
040 | a (SwePub)gud (SwePub)uu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Ladenvall, Per,d 1972u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sahlgrenska Acad, Dept Mol & Clin Med, Gothenburg, Sweden.4 aut0 (Swepub:gu)xladpe |
245 | 1 0 | a Low aerobic capacity in middle-aged men associated with increased mortality rates during 45 years of follow-up |
264 | c 2016-07-20 | |
264 | 1 | b Oxford University Press (OUP),c 2016 |
520 | a Background Low aerobic capacity has been associated with increased mortality in short-term studies. The aim of this study was to evaluate the predictive power of aerobic capacity for mortality in middle-aged men during 45-years of follow-up. Design The study design was a population-based prospective cohort study. Methods A representative sample from Gothenburg of men born in 1913 was followed from 50-99 years of age, with periodic medical examinations and data from the National Hospital Discharge and Cause of Death registers. At 54 years of age, 792 men performed an ergometer exercise test, with 656 (83%) performing the maximum exercise test. Results In Cox regression analysis, low predicted peak oxygen uptake (VO2max), smoking, high serum cholesterol and high mean arterial blood pressure at rest were significantly associated with mortality. In multivariable analysis, an association was found between predicted VO2max tertiles and mortality, independent of established risk factors. Hazard ratios were 0.79 (95% confidence interval (CI) 0.71-0.89; p<0.0001) for predicted VO2max, 1.01 (1.002-1.02; p<0.01) for mean arterial blood pressure, 1.13 (1.04-1.22; p<0.005) for cholesterol, and 1.58 (1.34-1.85; p<0.0001) for smoking. The variable impact (Wald's (2)) of predicted VO2max tertiles (15.3) on mortality was secondary only to smoking (31.4). The risk associated with low predicted VO2max was evident throughout four decades of follow-up. Conclusion In this representative population sample of middle-aged men, low aerobic capacity was associated with increased mortality rates, independent of traditional risk factors, including smoking, blood pressure and serum cholesterol, during more than 40 years of follow-up. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
653 | a Exercise testing | |
653 | a epidemiology | |
653 | a mortality | |
653 | a aerobic capacity | |
653 | a exercise capacity | |
653 | a coronary risk-evaluation | |
653 | a all-cause mortality | |
653 | a cardiorespiratory | |
653 | a fitness | |
653 | a physical-fitness | |
653 | a cardiovascular events | |
653 | a heart-disease | |
653 | a healthy-men | |
653 | a cause death | |
653 | a exercise | |
653 | a metaanalysis | |
653 | a Cardiovascular System & Cardiology | |
653 | a Exercise testing | |
700 | 1 | a Persson, Carina Ulla,d 1970u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation,Univ Gothenburg, Sahlgrenska Acad, Dept Clin Neurosci & Rehabil, Gothenburg, Sweden.4 aut0 (Swepub:gu)xperca |
700 | 1 | a Mandalenakis, Zacharias,d 1979u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sahlgrenska Acad, Dept Mol & Clin Med, Gothenburg, Sweden.4 aut0 (Swepub:gu)xmanza |
700 | 1 | a Wilhelmsen, Lars,d 1932u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sahlgrenska Acad, Dept Mol & Clin Med, Gothenburg, Sweden.4 aut0 (Swepub:gu)xwilhl |
700 | 1 | a Grimby, Gunnar,d 1933u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation,Univ Gothenburg, Sahlgrenska Acad, Dept Clin Neurosci & Rehabil, Gothenburg, Sweden.4 aut0 (Swepub:gu)xgrimg |
700 | 1 | a Svärdsudd, Kurtu Uppsala universitet,Allmänmedicin och preventivmedicin4 aut0 (Swepub:uu)kurtsvar |
700 | 1 | a Hansson, Per-Olof,d 1958u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sahlgrenska Acad, Dept Mol & Clin Med, Gothenburg, Sweden.4 aut0 (Swepub:gu)xhanpm |
710 | 2 | a Göteborgs universitetb Institutionen för medicin, avdelningen för molekylär och klinisk medicin4 org |
773 | 0 | t European Journal of Preventive Cardiologyd : Oxford University Press (OUP)g 23:14, s. 1557-1564q 23:14<1557-1564x 2047-4873x 2047-4881 |
856 | 4 8 | u https://gup.ub.gu.se/publication/244286 |
856 | 4 8 | u https://doi.org/10.1177/2047487316655466 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-305545 |
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