SwePub
Sök i LIBRIS databas

  Extended search

onr:"swepub:oai:gup.ub.gu.se/247574"
 

Search: onr:"swepub:oai:gup.ub.gu.se/247574" > Aggressive Posterio...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist
  • Lundgren, Pia,1967Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology,Section for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Clin Neurosci,Sect Ophthalmol, Gothenburg, Sweden (author)

Aggressive Posterior Retinopathy of Prematurity Is Associated with Multiple Infectious Episodes and Thrombocytopenia

  • Article/chapterEnglish2017

Publisher, publication year, extent ...

  • 2016-09-16
  • S. Karger AG,2017

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/247574
  • https://gup.ub.gu.se/publication/247574URI
  • https://doi.org/10.1159/000448161DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-83382URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-359813URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:134885285URI

Supplementary language notes

  • Language:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • © 2016 S. Karger AG, BaselBackground: The most severe form of rapidly progressing retinopathy of prematurity (ROP) is termed aggressive posterior ROP (APROP). APROP frequently causes severe visual impairment in affected preterm infants despite timely and appropriate laser treatment. Objectives: We investigated the postnatal characteristics associated with APROP development in a national Swedish cohort. Methods: This retrospective, 1:1 matched case-control study included all infants that developed APROP in zone 1 (n = 9) between 2008 and 2012. Control infants, matched for gestational age and birth weight, developed ROP no worse than stage 2 (n = 9). We retrieved data from medical records on infant birth characteristics, postnatal morbidities, and blood analyses from birth to the first ROP treatment. Infectious episodes included sepsis, C-reactive protein ≥10 mg/l, and other clinical signs of infection that required antibiotic treatment. A platelet count <100 × 109/l was considered to be thrombocytopenia. Results: All APROP cases postnatally developed at least two infectious episodes, one in the first month and one around the time of ROP diagnosis. All APROP cases exhibited thrombocytopenia in the first month, and 6/9 exhibited thrombocytopenia around the time of ROP diagnosis. Compared to the controls, APROP cases more frequently developed necrotizing enterocolitis (8/9 vs. 1/9; p < 0.01) and sepsis (9/9 vs. 3/9; p < 0.01), and they had significantly lower median platelet counts (90 × 109/l, range 4-459, vs. 158 × 109/l, range 20-500; p < 0.001). Conclusion: Multiple infectious episodes and thrombocytopenia, particularly around the time of ROP diagnosis, were associated with APROP development.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Lundberg, LinneaGothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology,Section for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Clin Neurosci,Sect Ophthalmol, Gothenburg, Sweden (author)
  • Hellgren, Gunnel,1961Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology,Section for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Clin Neurosci,Sect Ophthalmol, Gothenburg, Sweden(Swepub:gu)xhegun (author)
  • Holmström, Gerd,1951-Uppsala universitet,Oftalmiatrik(Swepub:uu)gerdholm (author)
  • Hård, Anna-Lena,1949Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology,Section for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Clin Neurosci,Sect Ophthalmol, Gothenburg, Sweden (author)
  • Smith, Lois E.Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA,Harvard Med Sch, Boston Childrens Hosp, Dept Ophthalmol, Boston, MA USA (author)
  • Wallin, AgnetaSt. Eriks Eye Hospital, University Hospital, Stockholm, Sweden,St Eriks Eye Hosp, Stockholm, Sweden (author)
  • Hallberg, BoubouKarolinska Institutet (author)
  • Hellström, Ann,1959Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology,Section for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Clin Neurosci,Sect Ophthalmol, Gothenburg, Sweden(Swepub:gu)xheann (author)
  • Göteborgs universitetInstitutionen för neurovetenskap och fysiologi (creator_code:org_t)

Related titles

  • In:Neonatology: S. Karger AG111:1, s. 79-851661-78001661-7819

Internet link

Find in a library

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view