Search: onr:"swepub:oai:gup.ub.gu.se/253436" >
Sensitive magnetic ...
Sensitive magnetic biodetection using magnetic multi-core nanoparticles and RCA coils
-
- Ahrentorp, Fredrik (author)
- RISE,Acreo
-
- Blomgren, Jakob (author)
- RISE,Acreo
-
- Jonasson, Christian (author)
- RISE,Acreo
-
show more...
-
- Sarwe, A. (author)
- RISE,Acreo
-
- Sepehri, Sobhan, 1986 (author)
- Chalmers tekniska högskola,Chalmers University of Technology,Chalmers University of Technology, Sweden
-
- Eriksson, Emil, 1990 (author)
- Chalmers tekniska högskola,Chalmers University of Technology,Chalmers University of Technology, Sweden
-
- Kalaboukhov, Alexei, 1975 (author)
- Chalmers tekniska högskola,Chalmers University of Technology,Chalmers University of Technology, Sweden
-
- Jesorka, Aldo, 1967 (author)
- Chalmers tekniska högskola,Chalmers University of Technology,Chalmers University of Technology, Sweden
-
- Winkler, Dag, 1957 (author)
- Chalmers tekniska högskola,Chalmers University of Technology,Chalmers University of Technology, Sweden
-
- Schneiderman, Justin F., 1979 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology,University of Gothenburg,Chalmers tekniska högskola,Chalmers University of Technology,University of Gothenburg, Sweden
-
- Nilsson, Mats (author)
- Stockholms universitet,Institutionen för biokemi och biofysik,Science for Life Laboratory (SciLifeLab),Stockholm University, Sweden
-
- Albert, J. (author)
- Karolinska Institutet
-
- Zardán Gómez de la Torre, Teresa (author)
- Uppsala universitet,Nanoteknologi och funktionella material
-
- Strømme, Maria, 1970- (author)
- Uppsala universitet,Nanoteknologi och funktionella material
-
Johansson, C. (author)
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2017
- 2017
- English.
-
In: Journal of Magnetism and Magnetic Materials. - : Elsevier BV. - 0304-8853 .- 1873-4766. ; 427, s. 14-18
- Related links:
-
https://gup.ub.gu.se...
-
show more...
-
https://doi.org/10.1...
-
https://research.cha...
-
https://urn.kb.se/re...
-
https://urn.kb.se/re...
-
https://urn.kb.se/re...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- We use functionalized iron oxide magnetic multi-core particles of 100 nm in size (hydrodynamic particle diameter) and AC susceptometry (ACS) methods to measure the binding reactions between the magnetic nanoparticles (MNPs) and bio-analyte products produced from DNA segments using the rolling circle amplification (RCA) method. We use sensitive induction detection techniques in order to measure the ACS response. The DNA is amplified via RCA to generate RCA coils with a specific size that is dependent on the amplification time. After about 75 min of amplification we obtain an average RCA coil diameter of about 1 mu m. We determine a theoretical limit of detection (LOD) in the range of 11 attomole (corresponding to an analyte concentration of 55 fM for a sample volume of 200 mu L) from the ACS dynamic response after the MNPs have bound to the RCA coils and the measured ACS readout noise. We also discuss further possible improvements of the LOD.
Subject headings
- NATURVETENSKAP -- Fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences (hsv//eng)
- NATURVETENSKAP -- Kemi -- Analytisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Analytical Chemistry (hsv//eng)
- NATURVETENSKAP -- Fysik -- Annan fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Other Physics Topics (hsv//eng)
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Nanoteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Nano-technology (hsv//eng)
Keyword
- Magnetic nanoparticles
- Magnetic multi-core particles
- AC susceptometry
- RCA coil
- Differential
- PARTICLES
- DIAGNOSTICS
- NANOBEADS
- SENSORS
- Materials Science
- Multidisciplinary
- Physics
- Condensed Matter
- RMANY
- V380
- P221
- Biodetection
- Teknisk fysik med inriktning mot nanoteknologi och funktionella material
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Ahrentorp, Fredr ...
-
Blomgren, Jakob
-
Jonasson, Christ ...
-
Sarwe, A.
-
Sepehri, Sobhan, ...
-
Eriksson, Emil, ...
-
show more...
-
Kalaboukhov, Ale ...
-
Jesorka, Aldo, 1 ...
-
Winkler, Dag, 19 ...
-
Schneiderman, Ju ...
-
Nilsson, Mats
-
Albert, J.
-
Zardán Gómez de ...
-
Strømme, Maria, ...
-
Johansson, C.
-
show less...
- About the subject
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Physical Science ...
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Chemical Science ...
-
and Analytical Chemi ...
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Physical Science ...
-
and Other Physics To ...
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Biological Scien ...
-
- ENGINEERING AND TECHNOLOGY
-
ENGINEERING AND ...
-
and Nano technology
- Articles in the publication
-
Journal of Magne ...
- By the university
-
University of Gothenburg
-
Chalmers University of Technology
-
Stockholm University
-
RISE
-
Uppsala University
-
Karolinska Institutet