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Green listed-a CRISPR screen tool

Panda, S. K. (author)
Boddul, S. V. (author)
Karolinska Institutet
Jimenez-Andrade, G. Y. (author)
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Jiang, L. (author)
Karolinska Institutet
Kasza, Z. (author)
Karolinska Institutet
Fernandez Ricaud, Luciano Francisco, 1975 (author)
Gothenburg University,Göteborgs universitet,Institutionen för marina vetenskaper,Department of marine sciences
Wermeling, F. (author)
Karolinska Institutet
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 (creator_code:org_t)
2016-12-19
2017
English.
In: Bioinformatics. - : Oxford University Press (OUP). - 1367-4803 .- 1367-4811. ; 33:7, s. 1099-1100
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Motivation: Genome editing using versions of the bacterial CRISPR/Cas9 system can be used to probe the function of selected genes in any organism.Green Listed is a web-based tool that rapidly designs custom CRISPR screens targeting sets of genes defined by the user. It could thus be used to design screens targeting for example all genes differentially expressed during a specific stimuli or all genes related to a specific pathway or function, as well as to generate targeted secondary screens following a large-scale screen.

Subject headings

NATURVETENSKAP  -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
NATURVETENSKAP  -- Kemi (hsv//swe)
NATURAL SCIENCES  -- Chemical Sciences (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)
NATURVETENSKAP  -- Data- och informationsvetenskap -- Programvaruteknik (hsv//swe)
NATURAL SCIENCES  -- Computer and Information Sciences -- Software Engineering (hsv//eng)

Keyword

human genome
activation
immunity

Publication and Content Type

ref (subject category)
art (subject category)

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