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Green listed-a CRIS...
Green listed-a CRISPR screen tool
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Panda, S. K. (author)
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- Boddul, S. V. (author)
- Karolinska Institutet
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Jimenez-Andrade, G. Y. (author)
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- Jiang, L. (author)
- Karolinska Institutet
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- Kasza, Z. (author)
- Karolinska Institutet
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- Fernandez Ricaud, Luciano Francisco, 1975 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för marina vetenskaper,Department of marine sciences
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- Wermeling, F. (author)
- Karolinska Institutet
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(creator_code:org_t)
- 2016-12-19
- 2017
- English.
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In: Bioinformatics. - : Oxford University Press (OUP). - 1367-4803 .- 1367-4811. ; 33:7, s. 1099-1100
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Abstract
Subject headings
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- Motivation: Genome editing using versions of the bacterial CRISPR/Cas9 system can be used to probe the function of selected genes in any organism.Green Listed is a web-based tool that rapidly designs custom CRISPR screens targeting sets of genes defined by the user. It could thus be used to design screens targeting for example all genes differentially expressed during a specific stimuli or all genes related to a specific pathway or function, as well as to generate targeted secondary screens following a large-scale screen.
Subject headings
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)
- NATURVETENSKAP -- Data- och informationsvetenskap -- Programvaruteknik (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences -- Software Engineering (hsv//eng)
Keyword
- human genome
- activation
- immunity
Publication and Content Type
- ref (subject category)
- art (subject category)
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