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Weight Loss in Patients with Dementia: Considering the Potential Impact of Pharmacotherapy

Franx, B. A. A. (author)
Department of Anatomy, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands
Arnoldussen, I. A. C. (author)
Department of Anatomy, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands
Kiliaan, A. J. (author)
Department of Anatomy, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands
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Gustafson, Deborah, 1966 (author)
Högskolan i Skövde,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology,Institutionen för hälsa och lärande,Forskningsspecialiseringen Hälsa och Lärande,Department of Neurology, Section for NeuroEpidemiology, State University of New York, Downstate Medical Center, USA / Neuropsychiatric Epidemiology Unit (EPINEP), Institute for Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden,Individ och samhälle (VIDSOC), Individual and Society
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 (creator_code:org_t)
2017-05-06
2017
English.
In: Drugs & Aging. - : Springer Science and Business Media LLC. - 1170-229X .- 1179-1969. ; 34:6, s. 425-436
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Unintentional body weight loss is common in patients with dementia and is linked to cognitive impairment and poorer disease outcomes. It is proposed that some dementia medications with market approval, while aiming to improve cognitive and functional outcomes of a patient with dementia, are associated with reported body weight or body mass index loss. This review presents evidence in the published literature on body weight loss in dementia, describes selected theories behind body weight loss, evaluates the potential impact of approved dementia pharmacotherapies on body weight, considers the potential role for medical foods, understands the potential influence of treatments for neuropsychiatric symptoms and signs, and finally, summarizes this important area.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Neurosciences (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences (hsv//eng)

Keyword

body-mass index
mild cognitive impairment
plasma leptin levels
alzheimers-disease patients
randomized controlled-trial
community-dwelling patients
transgenic mouse model
cholinesterase-inhibitors
older-adults
late-life
entice am
1989
age and ageing
v18
p158
Individual and Society VIDSOC

Publication and Content Type

ref (subject category)
art (subject category)

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By the author/editor
Franx, B. A. A.
Arnoldussen, I. ...
Kiliaan, A. J.
Gustafson, Debor ...
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Basic Medicine
and Neurosciences
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Health Sciences
Articles in the publication
Drugs & Aging
By the university
University of Gothenburg
University of Skövde

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