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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 10648naa a2201021 4500 | |
| 001 | oai:gup.ub.gu.se/255021 | |
| 003 | SwePub | |
| 008 | 240528s2017 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:umu-125053 | |
| 009 | oai:DiVA.org:uu-311300 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/2550212 URI |
| 024 | 7 | a https://doi.org/10.1093/ije/dyw1512 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1250532 URI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3113002 URI |
| 040 | a (SwePub)gud (SwePub)umud (SwePub)uu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Svanes, C.u Centre for International Health, University of Bergen, Norway; Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway; Department of Clinical Science, University of Bergen, Norway4 aut |
| 245 | 1 0 | a Father's environment before conception and asthma risk in his children: a multi-generation analysis of the Respiratory Health In Northern Europe study |
| 264 | c 2016-08-25 | |
| 264 | 1 | b Oxford University Press (OUP),c 2017 |
| 520 | a Background: Whereas it is generally accepted that maternal environment plays a key role in child health, emerging evidence suggests that paternal environment before conception also impacts child health. We aimed to investigate the association between children's asthma risk and parental smoking and welding exposures prior to conception. Methods: In a longitudinal, multi-country study, parents of 24 168 offspring aged 2-51 years provided information on their life-course smoking habits, occupational exposure to welding and metal fumes, and offspring's asthma before/after age 10 years and hay fever. Logistic regressions investigated the relevant associations controlled for age, study centre, parental characteristics (age, asthma, education) and clustering by family. Results: Non-allergic early-onset asthma (asthma without hay fever, present in 5.8%) was more common in the offspring with fathers who smoked before conception {odds ratio [OR] = 1.68 [95% confidence interval (CI) = 1.18-2.41]}, whereas mothers' smoking before conception did not predict offspring asthma. The risk was highest if father started smoking before age 15 years [3.24 (1.67-6.27)], even if he stopped more than 5 years before conception [2.68 (1.17-6.13)]. Fathers' pre-conception welding was independently associated with non-allergic asthma in his offspring [1.80 (1.29-2.50)]. There was no effect if the father started welding or smoking after birth. The associations were consistent across countries. Conclusions: Environmental exposures in young men appear to influence the respiratory health of their offspring born many years later. Influences during susceptible stages of spermatocyte development might be important and needs further investigation in humans. We hypothesize that protecting young men from harmful exposures may lead to improved respiratory health in future generations. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Arbetsmedicin och miljömedicin0 (SwePub)303032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Occupational Health and Environmental Health0 (SwePub)303032 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
| 653 | a asthma | |
| 653 | a epidemiology | |
| 653 | a smoking | |
| 653 | a occupational exposure | |
| 653 | a epigenesis | |
| 653 | a grandmaternal smoking patterns | |
| 653 | a sperm microrna content | |
| 653 | a slow growth | |
| 653 | a period | |
| 653 | a transgenerational responses | |
| 653 | a cigarette-smoking | |
| 653 | a tobacco-smoke | |
| 653 | a childhood asthma | |
| 653 | a germ-line | |
| 653 | a follow-up | |
| 653 | a exposure | |
| 653 | a Public | |
| 653 | a Environmental & Occupational Health | |
| 653 | a asthma | |
| 700 | 1 | a Koplin, J.u Centre for International Health, University of Bergen, Norway; School of Population and Global Health, University of Melbourne, Australia; Murdoch Childrens Research Institute, Melbourne, Australia4 aut |
| 700 | 1 | a Skulstad, S. M.u Department of Clinical Science, University of Bergen, Norway; Department of Obstetrics, Oslo University Hospital, Rikshospitalet, Oslo, Norway4 aut |
| 700 | 1 | a Johannessen, A.u Department of Clinical Science, University of Bergen, Norway; Centre for Clinical Research, Haukeland University Hospital, Bergen, Norway4 aut |
| 700 | 1 | a Jögi, Rainu Uppsala universitet,Lung- allergi- och sömnforskning,Lung Clinic, Foundation Tartu University Clinics, Tartu, Estonia; Department of Pulmonary Medicine, Tartu University, Estonia4 aut0 (Swepub:uu)raijo735 |
| 700 | 1 | a Benediktsdottir, B.u Department of Allergy, Respiratory Medicine and Sleep, Landspitali University Hospital, Reykjavik, Iceland; University of Iceland, Medical Faculty4 aut |
| 700 | 1 | a Bråbäck, Lennartu Umeå universitet,Yrkes- och miljömedicin,Occupational and Environmental Medicine, Department of Public Health and Clinical Medicine, Umeå University, Sweden4 aut0 (Swepub:umu)lebr0005 |
| 700 | 1 | a Carsin, A. E.u Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain4 aut |
| 700 | 1 | a Dharmage, S.u Department of Clinical Science, University of Bergen, Norway; School of Population and Global Health, University of Melbourne, Australia4 aut |
| 700 | 1 | a Dratva, J.u Centre for International Health, University of Bergen, Norway; Department of Epidemiology and Public Health, Gender & Health, Swiss Tropical and Public Health Institute, Basel University, Switzerland4 aut |
| 700 | 1 | a Forsberg, Bertilu Umeå universitet,Yrkes- och miljömedicin,Arcum,Occupational and Environmental Medicine, Department of Public Health and Clinical Medicine, Umeå University, Sweden4 aut0 (Swepub:umu)befo0001 |
| 700 | 1 | a Gislason, T.u Department of Allergy, Respiratory Medicine and Sleep, Landspitali University Hospital, Reykjavik, Iceland; University of Iceland, Medical Faculty4 aut |
| 700 | 1 | a Heinrich, J.u Institute of Epidemiology I, Helmholtz Zentrum, Munich, Germany4 aut |
| 700 | 1 | a Holm, Mathias,d 1969u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för arbets-och miljömedicin,Institute of Medicine, Department of Public Health and Community Medicine, Section of Occupational and environmental medicine,Occupational and Environmental Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xhomat |
| 700 | 1 | a Janson, Christeru Uppsala universitet,Lung- allergi- och sömnforskning4 aut0 (Swepub:uu)chrisjn |
| 700 | 1 | a Jarvis, D.u Faculty of Medicine, National Heart & Lung Institute, Imperial College, London, UK4 aut |
| 700 | 1 | a Jogi, R.4 aut |
| 700 | 1 | a Krauss-Etschmann, S.u Research Center Borstel, Leibniz- Center for Medicine and Biosciences, Divison of Experimental Asthma Research, University of Kiel, Germany4 aut |
| 700 | 1 | a Lindberg, Evau Uppsala universitet,Lung- allergi- och sömnforskning4 aut0 (Swepub:uu)evalb |
| 700 | 1 | a Macsali, F.u Department of Obstetrics and Gynecology, Haukeland, University Hospital, Bergen, Norway and4 aut |
| 700 | 1 | a Malinovschi, Andrei,d 1978-u Uppsala universitet,Klinisk fysiologi4 aut0 (Swepub:uu)anmal535 |
| 700 | 1 | a Modig, Larsu Umeå universitet,Yrkes- och miljömedicin,Centre for International Health, University of Bergen, Norway,Occupational and Environmental Medicine, Department of Public Health and Clinical Medicine, Umea ̊ University, Sweden4 aut0 (Swepub:umu)lasmog96 |
| 700 | 1 | a Norbäck, Danu Uppsala universitet,Arbets- och miljömedicin4 aut0 (Swepub:uu)dagnorba |
| 700 | 1 | a Omenaas, E.u Department of Clinical Science, University of Bergen, Norway; Centre for Clinical Research, Haukeland University Hospital, Bergen, Norway4 aut |
| 700 | 1 | a Saure, E. W.u Department of Clinical Science, University of Bergen, Norway4 aut |
| 700 | 1 | a Sigsgaard, T.u Department of Public Health, Aarhus University, Denmark4 aut |
| 700 | 1 | a Skorge, T. D.u Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway4 aut |
| 700 | 1 | a Svanes, O.4 aut |
| 700 | 1 | a Torén, Kjell,d 1952u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för arbets-och miljömedicin,Institute of Medicine, Department of Public Health and Community Medicine, Section of Occupational and environmental medicine,Occupational and Environmental Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden4 aut0 (Swepub:gu)xtorkj |
| 700 | 1 | a Torres, C.u Department of Clinical Science, University of Bergen, Norway4 aut |
| 700 | 1 | a Schlunssen, V.u Department of Public Health; Aarhus University, Denmark4 aut |
| 700 | 1 | a Real, F. G.u Department of Clinical Science, University of Bergen, Norway; Department of Obstetrics and Gynecology, Haukeland, University Hospital, Bergen, Norway4 aut |
| 700 | 1 | a Svanes, Øisteinu Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway; Department of Clinical Science, University of Bergen, Norway4 aut |
| 710 | 2 | a Centre for International Health, University of Bergen, Norway; Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway; Department of Clinical Science, University of Bergen, Norwayb Centre for International Health, University of Bergen, Norway; School of Population and Global Health, University of Melbourne, Australia; Murdoch Childrens Research Institute, Melbourne, Australia4 org |
| 773 | 0 | t International Journal of Epidemiologyd : Oxford University Press (OUP)g 46:1, s. 235-245q 46:1<235-245x 0300-5771x 1464-3685 |
| 856 | 4 | u https://academic.oup.com/ije/article-pdf/46/1/235/13733252/dyw151.pdf |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/255021 |
| 856 | 4 8 | u https://doi.org/10.1093/ije/dyw151 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-125053 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-311300 |
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