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The role of cholesterol metabolism and various steroid abnormalities in autism spectrum disorders: A hypothesis paper
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- Gillberg, Christopher, 1950 (author)
- Gothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre
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- Fernell, Elisabeth, 1948 (author)
- Gothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre
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- Kočovská, Eva, 1962 (author)
- Gothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre
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- Bourgeron, T. (author)
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- (creator_code:org_t)
- 2017-04-12
- 2017
- English.
- In: Autism Research. - : Wiley. - 1939-3792. ; 10:6, s. 1022-1044
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Based on evidence from the relevant research literature, we present a hypothesis that there may be a link between cholesterol, vitamin D, and steroid hormones which subsequently impacts on the development of at least some of the autisms [Coleman & Gillberg]. Our hypothesis, driven by the peer reviewed literature, posits that there may be links between cholesterol metabolism, which we will refer to as steroid metabolism and findings of steroid abnormalities of various kinds (cortisol, testosterone, estrogens, progesterone, vitamin D) in autism spectrum disorder (ASD). Further research investigating these potential links is warranted to further our understanding of the biological mechanisms underlying ASD. Autism Res2017. (c) 2017 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research. Autism Res 2017, 10: 1022-1044. (c) 2017 International Society for Autism Research, Wiley Periodicals, Inc.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Keyword
- autism
- cholesterol
- cortisol
- estrogens
- steroid hormones
- testosterone
- vitamin D
- LEMLI-OPITZ-SYNDROME
- CORTISOL CIRCADIAN-RHYTHMS
- MALE BRAIN THEORY
- VITAMIN-D
- TUBEROUS SCLEROSIS
- INTRANASAL OXYTOCIN
- FUNCTIONING
- CHILDREN
- SYSTEMATIC REVIEWS
- SALIVARY CORTISOL
- PRISMA STATEMENT
Publication and Content Type
- ref (subject category)
- art (subject category)
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- Minnis, Helen
- Bourgeron, T.
- Thompson, Lucy
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- Allely, Clare Sa ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
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- and Neurosciences
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- Autism Research
- By the university
- University of Gothenburg
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