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Further evidence fo...
Further evidence for the role of pregnancy-induced hypertension and other early life influences in the development of ADHD: results from the IDEFICS study
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- Pohlabeln, H. (author)
- Leibniz Inst Prevent Res & Epidemiol BIPS, Achterstr 30, D-28359 Bremen, Germany
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- Rach, S. (author)
- Leibniz Inst Prevent Res & Epidemiol BIPS, Achterstr 30, D-28359 Bremen, Germany
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- De Henauw, S. (author)
- Univ Ghent, Dept Publ Hlth, Fac Med & Hlth Sci, Ghent, Belgium
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- Eiben, Gabriele, 1960 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Sect Epidemiol & Social Med, Gothenburg, Sweden
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- Gwozdz, W. (author)
- Copenhagen Business Sch, Dept Intercultural Commun & Management, Ctr Corp Social Responsibil, Copenhagen, Denmark
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- Hadjigeorgiou, C. (author)
- Res & Educ Inst Child Hlth, Strovolos, Cyprus
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- Molnar, D. (author)
- Univ Pecs, Fac Med, Dept Paediat, Pecs, Hungary
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- Moreno, L. A. (author)
- Univ Zaragoza, IA2, Inst Invest Sanitaria Aragon IIS Aragon,GENUS Gro, Res Grp,Ctr Invest Biomed Red Fisiopatol Obesidad, Zaragoza, Spain
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- Russo, P. (author)
- CNR, Inst Food Sci, Unit Epidemiol & Populat Genet, Avellino, Italy
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- Veidebaum, T. (author)
- Natl Inst Hlth Dev, Tallinn, Estonia
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- Pigeot, I. (author)
- Leibniz Inst Prevent Res & Epidemiol BIPS, Achterstr 30, D-28359 Bremen, Germany
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(creator_code:org_t)
- 2017-03-03
- 2017
- English.
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In: European Child & Adolescent Psychiatry. - : Springer Science and Business Media LLC. - 1018-8827 .- 1435-165X. ; 26:8, s. 957-967
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Abstract
Subject headings
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- The aim of this study is to investigate whether in addition to established early risk factors other, less studied pre-, peri-, and postnatal influences, like gestational hypertension or neonatal respiratory disorders and infections, may increase a child's risk of developing attention-deficit/hyperactivity disorders (ADHD). In the IDEFICS study more than 18,000 children, aged 2-11.9 years, underwent extensive medical examinations supplemented by parental questionnaires on pregnancy and early childhood. The present analyses are restricted to children whose parents also completed a supplementary medical questionnaire (n = 15,577), including the question whether or not the child was ever diagnosed with ADHD. Multilevel multivariable logistic regression was used to assess the association between early life influences and the risk of ADHD. Our study confirms the well-known association between maternal smoking during pregnancy and a child's risk of ADHD. In addition, our study showed that children born to mothers younger than 20 years old were 3-4 times more likely to develop ADHD as compared to children born to mothers aged 25 years and older. Moreover, we found that children whose mothers suffered from pregnancy-induced hypertension had an approximately twofold risk of ADHD (OR 1.95; 95% CI 1.09-3.48). This also holds true for infections during the first 4 weeks after birth (OR 2.06; 95% CI 1.05-4.04). In addition, although not statistically significant, we observed a noticeable elevated risk estimate for neonatal respiratory disorders (OR 1.76; 95% CI 0.91-3.41). Hence, we recommend that these less often studied pre-, peri, and postnatal influences should get more attention when considering early indicators or predictors for ADHD in children. However, special study designs such as genetically sensitive designs may be needed to derive causal conclusions.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Keyword
- Attention-deficit/hyperactivity disorders
- European children cohort
- Gestational hypertension
- deficit hyperactivity disorder
- attention-deficit/hyperactivity
- disorder
- population-based cohort
- maternal smoking
- birth-weight
- worldwide prevalence
- gender-differences
- risk-factors
- school-age
- children
- Psychology
- Pediatrics
- Psychiatry
- Attention-deficit/hyperactivity disorders
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Pohlabeln, H.
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Rach, S.
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De Henauw, S.
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Eiben, Gabriele, ...
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Gwozdz, W.
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Hadjigeorgiou, C ...
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show more...
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Molnar, D.
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Moreno, L. A.
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Russo, P.
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Veidebaum, T.
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Pigeot, I.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Pediatrics
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SOCIAL SCIENCES
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and Psychology
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Psychiatry
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
- Articles in the publication
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European Child & ...
- By the university
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University of Gothenburg
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University of Skövde