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Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles
- Reiner, A. T. (author)
- Witwer, K. W. (author)
- van Balkom, B. W. M. (author)
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- de Beer, J. (author)
- Brodie, C. (author)
- Corteling, R. L. (author)
- Gimona, M. (author)
- Ibrahim, A. G. (author)
- de Kleijn, D. (author)
- Lai, C. P. (author)
- del Portillo, H. A. (author)
- Reischl, I. G. (author)
- Riazifar, M. (author)
- Salomon, C. (author)
- Tahara, H. (author)
- Toh, W. S. (author)
- Wauben, M. H. M. (author)
- Yang, V. K. (author)
- Yang, Y. J. (author)
- Yeo, R. W. Y. (author)
- Yin, H. (author)
- Giebel, B. (author)
- Rohde, E. (author)
- Lim, S. K. (author)
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- (creator_code:org_t)
- 2017-07-17
- 2017
- English.
- In: Stem Cells Translational Medicine. - : Oxford University Press (OUP). - 2157-6564 .- 2157-6580. ; 6:8
- Research review (peer-reviewed)
Abstract
Subject headings
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- Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as therapeutic entities, particularly in stem cell-related approaches, has underlined the need for standardization and coordination of development efforts. Members of the International Society for Extracellular Vesicles and the Society for Clinical Research and Translation of Extracellular Vesicles Singapore convened a Workshop on this topic to discuss the opportunities and challenges associated with development of EV-based therapeutics at the preclinical and clinical levels. This review outlines topic-specific action items that, if addressed, will enhance the development of best-practice models for EV therapies.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)
Keyword
- Stem cells
- Cellular therapy
- Clinical trials
- Clinical translation
- Extracellular vesicles
- Therapeutics
- MESENCHYMAL STROMAL CELLS
- HUMAN PLATELET LYSATE
- FETAL BOVINE SERUM
- EXOSOMES
- REGENERATION
- DELIVERY
- MICROVESICLES
- PLASMA
- CANCER
- NEED
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- Reiner, A. T.
- Witwer, K. W.
- van Balkom, B. W ...
- de Beer, J.
- Brodie, C.
- Corteling, R. L.
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- Gabrielsson, S.
- Gimona, M.
- Ibrahim, A. G.
- de Kleijn, D.
- Lai, C. P.
- Lötvall, Jan, 19 ...
- del Portillo, H. ...
- Reischl, I. G.
- Riazifar, M.
- Salomon, C.
- Tahara, H.
- Toh, W. S.
- Wauben, M. H. M.
- Yang, V. K.
- Yang, Y. J.
- Yeo, R. W. Y.
- Yin, H.
- Giebel, B.
- Rohde, E.
- Lim, S. K.
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