Search: onr:"swepub:oai:gup.ub.gu.se/261057" >
The Impact of Intro...
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Bruxvoort, K. J.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
(author)
The Impact of Introducing Malaria Rapid Diagnostic Tests on Fever Case Management: A Synthesis of Ten Studies from the ACT Consortium
- Article/chapterEnglish2017
Publisher, publication year, extent ...
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American Society of Tropical Medicine and Hygiene,2017
Numbers
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LIBRIS-ID:oai:gup.ub.gu.se/261057
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https://gup.ub.gu.se/publication/261057URI
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https://doi.org/10.4269/ajtmh.16-0955DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-345141URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:137451488URI
Supplementary language notes
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Since 2010, the World Health Organization has been recommending that all suspected cases of malaria be confirmed with parasite-based diagnosis before treatment. These guidelines represent a paradigm shift away from presumptive antimalarial treatment of fever. Malaria rapid diagnostic tests (mRDTs) are central to implementing this policy, intended to target artemisinin-based combination therapies (ACT) to patients with confirmed malaria and to improve management of patients with nonmalarial fevers. The ACT Consortium conducted ten linked studies, eight in sub-Saharan Africa and two in Afghanistan, to evaluate the impact of mRDT introduction on case management across settings that vary in malaria endemicity and healthcare provider type. This synthesis includes 562,368 outpatient encounters (study size range 2,400-432,513). mRDTs were associated with significantly lower ACT prescription (range 8-69% versus 20-100%). Prescribing did not always adhere to malaria test results; in several settings, ACTs were prescribed to more than 30% of test-negative patients or to fewer than 80% of test-positive patients. Either an antimalarial or an antibiotic was prescribed for more than 75% of patients across most settings; lower antimalarial prescription for malaria test-negative patients was partly offset by higher antibiotic prescription. Symptomatic management with antipyretics alone was prescribed for fewer than 25% of patients across all scenarios. In community health worker and private retailer settings, mRDTs increased referral of patients to other providers. This synthesis provides an overview of shifts in case management that may be expected with mRDT introduction and highlights areas of focus to improve design and implementation of future case management programs.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Leurent, B.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
(author)
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Chandler, C. I. R.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
(author)
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Elfving, KristinaGothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine(Swepub:gu)xelfkr
(author)
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Baiden, F.Ensign Coll Publ Hlth, Epidemiol, Kpong, Ghana.
(author)
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Bjorkman, A.Karolinska Institutet
(author)
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Burchett, H. E. D.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
(author)
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Clarke, S. E.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
(author)
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Cundill, B.Univ Leeds, Leeds Inst Clin Trials Res, Leeds, W Yorkshire, England.
(author)
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DiLiberto, D. D.
(author)
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Elfving, KristinaGothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine(Swepub:gu)xelfkr
(author)
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Goodman, C.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
(author)
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Hansen, K. S.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.;Univ Copenhagen, Hlth Serv Res, Copenhagen, Denmark.
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Kachur, S. P.US Ctr Dis Control & Prevent, Atlanta, GA USA.;CDC, Malaria Branch, Atlanta, GA 30333 USA.
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Lal, S.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
(author)
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Lalloo, D. G.Univ Liverpool Liverpool Sch Trop Med, Clin Sci & Int Publ Hlth, Liverpool, Merseyside, England.
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Leslie, T.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
(author)
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Magnussen, P.Univ Copenhagen, Ctr Med Parasitol, Copenhagen, Denmark.;Copenhagen Univ Hosp, Ctr Med Parasitol, Copenhagen, Denmark.;Univ Copenhagen, Dept Vet & Anim Sci, Copenhagen, Denmark.
(author)
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Mangham-Jefferies, L.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
(author)
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Mårtensson, Andreas,1963-Uppsala universitet,Internationell barnhälsa och nutrition(Swepub:uu)andma331
(author)
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Mayan, I.Hlth Protect Res Org, Clin Trials, Kabul, Afghanistan.
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Mbonye, A. K.Minist Hlth, Kampala, Uganda.;Makerere Univ, Sch Publ Hlth, Community Hlth & Behav Sci, Kampala, Uganda.
(author)
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Msellem, M. I.Zanzibar Minist Hlth, Zanzibar Malaria Eliminat Programme, Zanzibar, Tanzania.
(author)
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Onwujekwe, O. E.Univ Nigeria, Dept Pharmacol & Therapeut, Enugu, Nigeria.;Univ Nigeria, Pharmacol & Therapeut, Enugu Campus, Enugu, Nigeria.
(author)
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Owusu-Agyei, S.Kintampo Hlth Res Ctr, Kintampo, Ghana.
(author)
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Rowland, M. W.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
(author)
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Shakely, D.Karolinska Inst, Stockholm, Sweden.;Karolinska Inst, Ctr Malaria Res, Stockholm, Sweden.;Univ Gothenburg, Sahlgrenska Acad, Hlth Metr, Gothenburg, Sweden.
(author)
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Staedke, S. G.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
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Vestergaard, L. S.Univ Copenhagen, Ctr Med Parasitol, Copenhagen, Denmark.;Copenhagen Univ Hosp, Copenhagen, Denmark.;Statens Serum Inst, Dept Infect Dis Epidemiol & Prevent, Copenhagen, Denmark.
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Webster, J.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
(author)
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Whitty, C. J. M.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
(author)
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Wiseman, V. L.London Sch Hyg & Trop Med, 15-17 Tavistock Pl, London WC1H 9SH, England.;Univ New South Wales, Sch Publ Hlth & Community Med, Sydney, NSW, Australia.
(author)
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Yeung, S.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
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Schellenberg, D.London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.
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Hopkins, H.
(author)
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London Sch Hyg & Trop Med, Global Hlth & Dev, London, England.Institutionen för biomedicin, avdelningen för infektionssjukdomar
(creator_code:org_t)
Related titles
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In:Am J Trop Med Hyg: American Society of Tropical Medicine and Hygiene97:4, s. 1170-11790002-96371476-1645
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In:The American Journal of Tropical Medicine and Hygiene: American Society of Tropical Medicine and Hygiene97:4, s. 1170-11791476-1645
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Bruxvoort, K. J.
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Leurent, B.
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Chandler, C. I. ...
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Elfving, Kristin ...
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Baiden, F.
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Bjorkman, A.
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show more...
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Burchett, H. E. ...
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Clarke, S. E.
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Cundill, B.
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DiLiberto, D. D.
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Goodman, C.
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Hansen, K. S.
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Kachur, S. P.
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Lal, S.
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Lalloo, D. G.
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Leslie, T.
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Magnussen, P.
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Mangham-Jefferie ...
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Mårtensson, Andr ...
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Mayan, I.
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Mbonye, A. K.
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Msellem, M. I.
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Onwujekwe, O. E.
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Owusu-Agyei, S.
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Rowland, M. W.
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Shakely, D.
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Staedke, S. G.
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Vestergaard, L. ...
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Webster, J.
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Whitty, C. J. M.
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Wiseman, V. L.
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Yeung, S.
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Schellenberg, D.
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Hopkins, H.
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University of Gothenburg
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Uppsala University
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Karolinska Institutet