Histomorphometric analyses of area fraction of different ratios of Bio-Oss((R)) and bone prior to grafting procedures - An in vitro study to demonstrate a baseline

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Histomorphometric analyses of area fraction of different ratios of Bio-Oss((R)) and bone prior to grafting procedures - An in vitro study to demonstrate a baseline

Aludden, H. (author): Aalborg Univ Hosp, Dept Oral & Maxillofacial Surg, Aalborg, Denmark.

Dahlin, Anna (author): Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials,Univ Gothenburg, BIOMATCELL VINN Excellence Ctr, Inst Surg Sci, Dept Biomat,Sahlgrenska Acad, Gothenburg, Sweden.

Starch-Jensen, T. (author): Aalborg Univ Hosp, Dept Oral & Maxillofacial Surg, Aalborg, Denmark.

Dahlin, Christer, 1959 (author): Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials,Univ Gothenburg, BIOMATCELL VINN Excellence Ctr, Inst Surg Sci, Dept Biomat,Sahlgrenska Acad, Gothenburg, Sweden.;NU Hosp Org, Dept Oral & Maxillofacial Surg, Trollhattan, Sweden.

Mordenfeld, Arne (author): Uppsala universitet,Centrum för klinisk forskning, Gävleborg,Käkkirurgi,Publ Hlth Serv, Dept Oral & Maxillofacial Surg, Gavle, Sweden

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Aalborg Univ Hosp, Dept Oral & Maxillofacial Surg, Aalborg, Denmark Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap (creator_code:org_t)

2017-10-27
2018
English.
In: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 29:2, s. 185-191

Related links:: https://gup.ub.gu.se...; show more...; https://doi.org/10.1...; https://urn.kb.se/re...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

ObjectiveThe objective of this study was to estimate the area fraction of different ratios of Bio-Oss((R)) and bone, prior to grafting in an in vitro model to demonstrate a histomorphometric baseline. MethodsBio-Oss((R)) particles were mixed with autogenous bone from pig jaw in three different ratios (50:50, 80:20 and 100:0) and packed in rice paper in a standardized procedure. Histomorphometric analyses were performed in 25 specimens and 74 regions of interest. The area percentage of Bio-Oss((R)), bone, and non-mineralized tissue (NMT) were calculated. Results were reported as mean values and 95% confidence interval (CI). ResultsThe mean area fraction of Bio-Oss((R)) was 20.6% (CI: 18.2-23) in the 50:50 mixture, 33.6% (CI: 29.7-37.6) in the 80:20 mixture, and 43.4% (CI: 40.5-46.3) in the 100:0 mixture. The mean area fraction of NMT was 60.5% (CI: 57.9-63.1) in the 50:50 mixture, 59.6% (CI: 56.4-62.7) in the 80:20 mixture, and 56.6% (CI: 53.7-59.5) in the 100:0 mixture. The mean area fraction of bone was 18.9% (CI: 16.9-20.9) in the 50:50 mixture and 6.8% (CI: 5-8.6) in the 80:20 mixture. ConclusionThere is a great difference in the clinically estimated percentage and the histomorphometrically evaluated percentage of Bio-Oss((R)) at baseline, prior to grafting. The area fraction of different tissues presented in this study may be beneficial as guidance for histomorphometrical baseline calculations when different mixtures of Bio-Oss((R)) and autogenous bone are used as grafting materials.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)

Keyword

alveolar ridge augmentation
bone substitute
dental implants
histology
sinus floor augmentation
anorganic bovine bone
sinus floor augmentation
horizontal ridge
augmentation
particulated autogenous bone
prospective case series
mineral bio-oss
implant placement
deproteinized bovine
clinical-trial
histologic evaluation
Dentistry
Oral Surgery & Medicine
Engineering
alveolar ridge augmentation

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By the author/editor: Aludden, H.; Dahlin, Anna; Starch-Jensen, T ...; Dahlin, Christer ...; Mordenfeld, Arne

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Dentistry

Articles in the publication: Clinical Oral Im ...

By the university: University of Gothenburg; Uppsala University

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