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Sleep disturbances ...
Sleep disturbances and dementia risk: A multicenter study
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- Sindi, S. (author)
- Stockholms universitet,Karolinska Institutet,Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Karolinska Institutet, Sweden; Imperial College London, United Kingdom
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- Kåreholt, Ingemar, 1960- (author)
- Stockholms universitet,Jönköping University,Karolinska Institutet,HHJ, Institutet för gerontologi,HHJ. ARN-J (Aging Research Network - Jönköping),Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Jönköping University, Sweden
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- Johansson, Lena, 1972 (author)
- Gothenburg University,Göteborgs universitet,Centrum för åldrande och hälsa (AgeCap),Centre for Ageing and Health (Agecap),Institute of Neuroscience and Physiology, Center for Health and Ageing AGECAP, Sahlgrenska Academy, University of Gothenburg, Sweden
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- Skoog, Johan, 1985 (author)
- Gothenburg University,Göteborgs universitet,Psykologiska institutionen,Centrum för åldrande och hälsa (AgeCap),Department of Psychology,Centre for Ageing and Health (Agecap),Institute of Neuroscience and Physiology, Center for Health and Ageing AGECAP, Sahlgrenska Academy, University of Gothenburg, Sweden
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- Sjoberg, L. (author)
- Stockholms universitet,Karolinska Institutet,Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
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- Wang, Hui-Xin (author)
- Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Stressforskningsinstitutet
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- Johansson, Boo (author)
- Gothenburg University,Göteborgs universitet,Centrum för åldrande och hälsa (AgeCap),Centre for Ageing and Health (Agecap),Department of Psychology, Center for Health and Ageing AGECAP, University of Gothenburg, Sweden
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- Fratiglioni, L. (author)
- Stockholms universitet,Karolinska Institutet,Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Stockholm Gerontology Research Center, Sweden
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- Soininen, H. (author)
- Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland
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- Solomon, A. (author)
- Karolinska Institutet,Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
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- Skoog, Ingmar, 1954 (author)
- Gothenburg University,Göteborgs universitet,Centrum för åldrande och hälsa (AgeCap),Centre for Ageing and Health (Agecap),Institute of Neuroscience and Physiology, Center for Health and Ageing AGECAP, Sahlgrenska Academy, University of Gothenburg, Sweden.
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- Kivipelto, M. (author)
- Karolinska Institutet,Neuroepidemiology and Ageing Research Unit, School of Public Health, Imperial College London, United Kingdom
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(creator_code:org_t)
- 2018-07-17
- 2018
- English.
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In: Alzheimers & Dementia. - : Wiley. - 1552-5260 .- 1552-5279. ; 14:10, s. 1235-1242
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Abstract
Subject headings
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- Introduction: Few longitudinal studies assessed whether sleep disturbances are associated with dementia risk. Methods: Sleep disturbances were assessed in three population-based studies (H70 study and Kungsholmen Project [Sweden]; Cardiovascular Risk Factors, Aging and Dementia study [Finland]). Late-life baseline analyses (3-10 years follow-up) used all three studies (N = 1446). Baseline ages 70 years (Cardiovascular Risk Factors, Aging and Dementia, H70), and approximate to 84 years (Kungsholmen Project). Midlife baseline (age approximate to 50 years) analyses used Cardiovascular Risk Factors, Aging and Dementia (21 and 32 years follow-up) (N = 1407). Results: Midlife insomnia (fully adjusted hazard ratio = 1.24, 95% confidence interval = 1.02-1.50) and late-life terminal insomnia (fully adjusted odds ratio = 1.94, 95% confidence interval = 1.08-3.49) were associated with a higher dementia risk. Late-life long sleep duration (>9 hours) was also associated with an increased dementia risk (adjusted odds ratio = 3.98, 95% confidence interval = 1.87-8.48). Discussion: Midlife insomnia and late-life terminal insomnia or long sleep duration were associated with a higher late-life dementia risk. (C) 2018 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Keyword
- Sleep disturbances
- Insomnia
- Sleep duration
- Dementia
- self-reported sleep
- alzheimers-disease
- daytime sleepiness
- incident
- dementia
- cognitive decline
- heart-disease
- duration
- disorders
- deprivation
- health
- Neurosciences & Neurology
- Dementia
- Geriatrics
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Sindi, S.
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Kåreholt, Ingema ...
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Johansson, Lena, ...
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Skoog, Johan, 19 ...
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Sjoberg, L.
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Wang, Hui-Xin
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Johansson, Boo
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Fratiglioni, L.
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Soininen, H.
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Solomon, A.
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Skoog, Ingmar, 1 ...
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Kivipelto, M.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Geriatrics
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Neurology
- Articles in the publication
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Alzheimers & Dem ...
- By the university
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University of Gothenburg
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Karolinska Institutet
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Jönköping University
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Stockholm University