Search: onr:"swepub:oai:gup.ub.gu.se/272814" >
Multidisciplinary d...
Multidisciplinary development of the Geriatric Core Dataset for clinical research in older patients with cancer: A French initiative with international survey
-
Paillaud, E. (author)
-
Soubeyran, P. (author)
-
Caillet, P. (author)
-
show more...
-
Cudennec, T. (author)
-
Brain, E. (author)
-
Terret, C. (author)
-
Etchepare, F. (author)
-
Mourey, L. (author)
-
Aparicio, T. (author)
-
Pamoukdjian, F. (author)
-
- Audisio, Riccardo A (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
-
Rostoft, S. (author)
-
Hurria, A. (author)
-
Bellera, C. (author)
-
Mathoulin-Pelissier, S. (author)
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2018
- 2018
- English.
-
In: European Journal of Cancer. - : Elsevier BV. - 0959-8049. ; 103, s. 61-68
- Related links:
-
https://gup.ub.gu.se...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Background: To define a core set of geriatric data to be methodically collected in clinical cancer trials of older adults, enabling comparison across trials. Patients and methods: Following a consensus approach, a panel of 14 geriatricians from oncology clinics identified seven domains of importance in geriatric assessment. Based on the international recommendations, geriatricians selected the mostly commonly used tools/items for geriatric assessment by domain (January-October 2015). The Geriatric Core Dataset (G-CODE) was progressively developed according to RAND appropriateness ratings and feedback during three successive Delphi rounds (July-September 2016). The face validity of the G-CODE was assessed with two large panels of health professionals (55 national and 42 international experts) involved both in clinical practice and cancer trials (March-September 2017). Results and discussion: After the last Delphi round, the tools/items proposed for the G-CODE were the following: (1) social assessment: living alone or support requested to stay at home; (2) functional autonomy: Activities of Daily Living (ADL) questionnaire and short instrumental ADL questionnaire; (3) mobility: Timed Up and Go test; (4) nutrition: weight loss during the past 6 months and body mass index; (5) cognition: Mini-Cog test; (6) mood: mini-Geriatric Depression Scale and (7) comorbidity: updated Charlson Comorbidity Index. More than 70% of national experts (42 from 20 cities) and international experts (31 from 13 countries) participated. National and international surveys showed good acceptability of the G-CODE. Specific points discussed included age-year cut-off, threshold of each tool/item and information about social support, but no additional item was proposed. Conclusion: We achieved formal consensus on a set of geriatric data to be collected in cancer trials of older patients. The dissemination and prospective use of the G-CODE is needed to assess its utility. (C) 2018 Elsevier Ltd. All rights reserved.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- Clinical trials
- Data set
- Delphi consensus
- Geriatric assessment
- Cancer
- Older patients
- elderly-patients
- 1st-line chemotherapy
- task-force
- feasibility
- depression
- oncology
- methodology
- validation
- predictors
- dementia
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Paillaud, E.
-
Soubeyran, P.
-
Caillet, P.
-
Cudennec, T.
-
Brain, E.
-
Terret, C.
-
show more...
-
Etchepare, F.
-
Mourey, L.
-
Aparicio, T.
-
Pamoukdjian, F.
-
Audisio, Riccard ...
-
Rostoft, S.
-
Hurria, A.
-
Bellera, C.
-
Mathoulin-Peliss ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cancer and Oncol ...
- Articles in the publication
-
European Journal ...
- By the university
-
University of Gothenburg