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Chronic kidney dise...
Chronic kidney disease in European patients with obstructive sleep apnea: the ESADA cohort study
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Marrone, Oreste (author)
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Battaglia, Salvatore (author)
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Steiropoulos, Paschalis (author)
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Basoglu, Ozen K. (author)
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Kvamme, John A. (author)
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Ryan, Silke (author)
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Pepin, Jean Louis (author)
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Verbraecken, Johan (author)
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- Grote, Ludger, 1964 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine
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- Hedner, Jan A, 1953 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine
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Bonsignore, Maria R. (author)
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Anttalainen, Ulla (author)
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Saaresranta, Tarja (author)
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Barbé, Ferran (author)
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Tasbakan, Sezai (author)
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Bielicki, Piotr (author)
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Kumor, Marta (author)
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Dumitrascu, Rio (author)
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Schulz, Richard (author)
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Escourrou, Pierre (author)
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Roisman, Gabriel (author)
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Fietze, Ingo (author)
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Penzel, Thomas (author)
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Kent, Brian D. (author)
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McNicholas, Walter T. (author)
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Lévy, Patrick (author)
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Pépin, Jean Louis (author)
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Tamisier, Renaud (author)
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Lavie, Lena (author)
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Lavie, Peretz (author)
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Lombardi, Carolina (author)
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Parati, Gianfranco (author)
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Masa, Juan Fernando (author)
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Montserrat, Josep M. (author)
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Pataka, Athanasia (author)
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Plywaczewski, Robert (author)
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Sliwinski, Pawel (author)
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Pretl, Martin (author)
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Riha, Renata (author)
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Rodenstein, Daniel (author)
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Tkacova, Ruzena (author)
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Varoneckas, Giedvar (author)
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Vrints, Heleen (author)
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Vitols, Audrey (author)
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(creator_code:org_t)
- 2016-05-18
- 2016
- English.
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In: Journal of Sleep Research. - : Wiley. - 0962-1105 .- 1365-2869. ; 25, s. 739-745
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https://doi.org/10.1...
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Abstract
Subject headings
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- © 2016 European Sleep Research Society The cross-sectional relationship of obstructive sleep apnea with moderate to severe chronic kidney disease, defined as an estimated glomerular filtration rate <60mLmin−1∙1.73m−2, was investigated in a large cohort of patients with suspected obstructive sleep apnea studied by nocturnal polysomnography or cardiorespiratory polygraphy. Data were obtained from the European Sleep Apnea Database, where information from unselected adult patients with suspected obstructive sleep apnea afferent to 26 European sleep centres had been prospectively collected. Both the Modification of Diet in Renal Disease and the Chronic Kidney Disease-Epidemiology Collaboration equations were used for the assessment of estimated glomerular filtration rate. The analysed sample included 7700 subjects, 71% male, aged 51.9±12.5years. Severe obstructive sleep apnea (apnea–hypopnea index ≥30) was found in 34% of subjects. The lowest nocturnal oxygen saturation was 81±10.2%. Chronic kidney disease prevalence in the whole sample was 8.7% or 6.1%, according to the Modification of Diet in Renal Disease or the Chronic Kidney Disease-Epidemiology Collaboration equations, respectively. Subjects with lower estimated glomerular filtration rate were older, more obese, more often female, had worse obstructive sleep apnea and more co-morbidities (P<0.001, each). With both equations, independent predictors of estimated glomerular filtration rate <60 were: chronic heart failure; female gender; systemic hypertension; older age; higher body mass index; and worse lowest nocturnal oxygen saturation. It was concluded that in obstructive sleep apnea, chronic kidney disease is largely predicted by co-morbidities and anthropometric characteristics. In addition, severe nocturnal hypoxaemia, even for only a small part of the night, may play an important role as a risk factor for kidney dysfunction.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Keyword
- epidemiology
- hypoxia
- nephropathy
Publication and Content Type
- ref (subject category)
- art (subject category)
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Marrone, Oreste
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Battaglia, Salva ...
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Steiropoulos, Pa ...
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Basoglu, Ozen K.
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Kvamme, John A.
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Ryan, Silke
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show more...
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Pepin, Jean Loui ...
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Verbraecken, Joh ...
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Grote, Ludger, 1 ...
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Hedner, Jan A, 1 ...
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Bonsignore, Mari ...
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Anttalainen, Ull ...
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Saaresranta, Tar ...
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Barbé, Ferran
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Tasbakan, Sezai
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Bielicki, Piotr
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Kumor, Marta
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Dumitrascu, Rio
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Schulz, Richard
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Escourrou, Pierr ...
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Roisman, Gabriel
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Fietze, Ingo
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Penzel, Thomas
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Kent, Brian D.
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McNicholas, Walt ...
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Lévy, Patrick
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Pépin, Jean Loui ...
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Tamisier, Renaud
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Lavie, Lena
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Lavie, Peretz
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Lombardi, Caroli ...
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Parati, Gianfran ...
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Masa, Juan Ferna ...
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Montserrat, Jose ...
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Pataka, Athanasi ...
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Plywaczewski, Ro ...
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Sliwinski, Pawel
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Pretl, Martin
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Riha, Renata
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Rodenstein, Dani ...
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Tkacova, Ruzena
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Varoneckas, Gied ...
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Vrints, Heleen
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Vitols, Audrey
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Urology and Neph ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
- Articles in the publication
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Journal of Sleep ...
- By the university
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University of Gothenburg