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Prevalence of under...
Prevalence of underweight, overweight, and obesity in children and adolescents with type 1 diabetes: Data from the international SWEET registry.
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Maffeis, Claudio (author)
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Birkebaek, Niels H (author)
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Konstantinova, Maia (author)
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Schwandt, Anke (author)
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Vazeou, Andriani (author)
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Casteels, Kristina (author)
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Jali, Sujata (author)
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Limbert, Catarina (author)
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Pundziute-Lycka, Auste (author)
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Toth-Heyn, Peter (author)
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de Beaufort, Carine (author)
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Sumnik, Zdenek (author)
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Cherubini, Valentino (author)
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Svensson, Jannet (author)
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Pacaud, Daniele (author)
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Kanaka-Gantenbein, Christina (author)
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Shalitin, Shlomit (author)
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Bratina, Natasa (author)
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- Hanås, Ragnar, 1951 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics
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Alonso, Guy T (author)
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Poran, Luxmi (author)
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Pereira, Ana L (author)
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Marigliano, Marco (author)
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(creator_code:org_t)
- 2018-08-22
- 2018
- English.
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In: Pediatric diabetes. - : Hindawi Limited. - 1399-5448 .- 1399-543X. ; 19:7, s. 1211-1220
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Abstract
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- To assess the prevalence of underweight (UW), overweight (OW), and obesity in children and adolescents with type 1 diabetes (T1D).An international cross-sectional study including 23026 T1D children (2-18 years, duration of diabetes ≥1year) participating in the SWEET prospective, multicenter diabetes registry. Body mass index SD score (BMI-SDS) was calculated using the World Health Organization BMI charts. Children were categorized as UW (BMI-SDS<-2SD), OW (+1SD+2SD). Hierarchic regression models were applied with adjustment for sex, age, and duration of diabetes.The prevalence of UW, OW, and obesity was: 1.4%, 22.3%, and 7.3% in males and 0.6%, 27.2%, and 6.8% in females. Adjusted BMI-SDS was significantly higher in females than in males (mean±SEM: 0.54±0.05 vs 0.40±0.05, P<0.0001). In males, BMI-SDS significantly decreased by age (P<0.0001) in the first three age categories 0.61±0.06 (2 to <10years), 0.47±0.06 (10 to <13 years), 0.34±0.05 (13 to <16 years). In females, BMI-SDS showed a U-shaped distribution by age (P<0.0001): 0.54±0.04 (2 to <10years), 0.39±0.04 (10 to <13 years), 0.55±0.04 (13 to <16 years). BMI-SDS increased by diabetes duration (<2years: 0.38±0.05, 2 to <5years: 0.44±0.05, and ≥5years: 0.50±0.05, P<0.0001). Treatment modality did not affect BMI-SDS. Adjusted HbA1c was significantly higher in females than in males (8.20%±0.10% vs 8.06%±0.10%, P<0.0001). In both genders, the association between HbA1c and BMI-SDS was U-shaped with the highest HbA1c in the UW and obesity groups.The high rate of OW and obesity (31.8%) emphasize the need for developing further strategies to prevent and treat excess fat accumulation in T1D.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
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- ref (subject category)
- art (subject category)
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- By the author/editor
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Maffeis, Claudio
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Birkebaek, Niels ...
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Konstantinova, M ...
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Schwandt, Anke
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Vazeou, Andriani
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Casteels, Kristi ...
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show more...
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Jali, Sujata
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Limbert, Catarin ...
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Pundziute-Lycka, ...
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Toth-Heyn, Peter
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de Beaufort, Car ...
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Sumnik, Zdenek
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Cherubini, Valen ...
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Svensson, Jannet
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Pacaud, Daniele
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Kanaka-Gantenbei ...
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Shalitin, Shlomi ...
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Bratina, Natasa
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Hanås, Ragnar, 1 ...
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Alonso, Guy T
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Poran, Luxmi
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Pereira, Ana L
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Marigliano, Marc ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
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Pediatric diabet ...
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University of Gothenburg