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- Wiklander, O. P. B.Karolinska Institutet (author)
Advances in therapeutic applications of extracellular vesicles
- Article/chapterEnglish2019
Publisher, publication year, extent ...
- American Association for the Advancement of Science (AAAS),2019
Numbers
- LIBRIS-ID:oai:gup.ub.gu.se/281162
- https://gup.ub.gu.se/publication/281162URI
- https://doi.org/10.1126/scitranslmed.aav8521DOI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:140916699URI
Supplementary language notes
- Language:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Extracellular vesicles (EVs) are nanometer-sized, lipid membrane-enclosed vesicles secreted by most, if not all, cells and contain lipids, proteins, and various nucleic acid species of the source cell. EVs act as important mediators of intercellular communication that influence both physiological and pathological conditions. Given their ability to transfer bioactive components and surmount biological barriers, EVs are increasingly being explored as potential therapeutic agents. EVs can potentiate tissue regeneration, participate in immune modulation, and function as potential alternatives to stem cell therapy, and bioengineered EVs can act as delivery vehicles for therapeutic agents. Here, we cover recent approaches and advances of EV-based therapies.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Cell- och molekylärbiologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Cell and Molecular Biology hsv//eng
- mesenchymal stromal cells
- exosome-mediated delivery
- dendritic cells
- drug-delivery
- gene delivery
- in-vitro
- neutralizing antibodies
- transferrin receptor
- membrane-vesicles
- immune-responses
Added entries (persons, corporate bodies, meetings, titles ...)
- Brennan, M. A. (author)
- Lötvall, Jan,1956Gothenburg University,Göteborgs universitet,Krefting Research Centre,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition(Swepub:gu)xlotja (author)
- Breakefield, X. O. (author)
- El Andaloussi, S.Karolinska Institutet (author)
- Karolinska InstitutetKrefting Research Centre (creator_code:org_t)
Related titles
- In:Science Translational Medicine: American Association for the Advancement of Science (AAAS)11:4921946-62341946-6242
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