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Advances in therape...
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Wiklander, O. P. B.Karolinska Institutet
(author)
Advances in therapeutic applications of extracellular vesicles
- Article/chapterEnglish2019
Publisher, publication year, extent ...
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American Association for the Advancement of Science (AAAS),2019
Numbers
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LIBRIS-ID:oai:gup.ub.gu.se/281162
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https://gup.ub.gu.se/publication/281162URI
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https://doi.org/10.1126/scitranslmed.aav8521DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:140916699URI
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Extracellular vesicles (EVs) are nanometer-sized, lipid membrane-enclosed vesicles secreted by most, if not all, cells and contain lipids, proteins, and various nucleic acid species of the source cell. EVs act as important mediators of intercellular communication that influence both physiological and pathological conditions. Given their ability to transfer bioactive components and surmount biological barriers, EVs are increasingly being explored as potential therapeutic agents. EVs can potentiate tissue regeneration, participate in immune modulation, and function as potential alternatives to stem cell therapy, and bioengineered EVs can act as delivery vehicles for therapeutic agents. Here, we cover recent approaches and advances of EV-based therapies.
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Brennan, M. A.
(author)
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Lötvall, Jan,1956Gothenburg University,Göteborgs universitet,Krefting Research Centre,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition(Swepub:gu)xlotja
(author)
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Breakefield, X. O.
(author)
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El Andaloussi, S.Karolinska Institutet
(author)
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Karolinska InstitutetKrefting Research Centre
(creator_code:org_t)
Related titles
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In:Science Translational Medicine: American Association for the Advancement of Science (AAAS)11:4921946-62341946-6242
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