SwePub
Sök i LIBRIS databas

  Extended search

onr:"swepub:oai:gup.ub.gu.se/282904"
 

Search: onr:"swepub:oai:gup.ub.gu.se/282904" > Sensitivity to chan...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist
  • Weis, J. (author)

Sensitivity to change of the EORTC quality of life module measuring cancer-related fatigue (EORTC QlQ-Fa12): Results from the international psychometric validation

  • Article/chapterEnglish2019

Publisher, publication year, extent ...

  • 2019-07-09
  • Wiley,2019

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/282904
  • https://gup.ub.gu.se/publication/282904URI
  • https://doi.org/10.1002/pon.5151DOI

Supplementary language notes

  • Language:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Objective The European Organisation for Research and Treatment of Cancer Quality of Life Group (EORTC QLG) has developed a multidimensional instrument measuring cancer-related fatigue, the EORTC QLQ-FA12. The analysis of sensitivity to change is an essential part of psychometric validation. With this study, we investigated the EORTC QLQ-FA12's sensitivity to change. Methods The methodology follows the EORTC guidelines of EORTC QLG for phase IV validation of modules. We included cancer patients undergoing curative and palliative treatment at t1 and followed them up prospectively over the course of their treatment (t2) and 4 weeks after completion of treatment (t3). Data were collected prospectively at 17 sites in 11 countries. Sensitivity to change was investigated using analysis of variance. Results A total sample of 533 patients was enrolled with various tumour types, different stages of cancer, and receiving either curative treatment (n=311) or palliative treatment (n=222). Over time all fatigue scores were significantly higher in the palliative treatment group compared with the curative group (p < .001). Physical fatigue increased with medium effect size over the course of treatment in the curative group (standardized response mean [SRM] (t1,t2) = 0.44]. After treatment physical [SRM (t2,t3) = 0.39], emotional [SRM (t2,t3)= 0.28] and cognitive fatigue (SRM [t2,t3] = 0.22) declined significantly in the curative group. In the palliative group, emotional (SRM [t2,t3] = 0.18) as well as cognitive [SRM [t2,t3] = 0.26) fatigue increases significantly. Conclusions The EORTC-QLQ-FA12 proved to identify clinically significant changes in fatigue in the course of curative and palliative cancer treatment.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Wirtz, M. A. (author)
  • Tomaszewski, K. A. (author)
  • Hammerlid, Eva,1957Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology(Swepub:gu)xhamev (author)
  • Arraras, J. I. (author)
  • Conroy, T. (author)
  • Lanceley, A. (author)
  • Schmidt, H. (author)
  • Singer, S. (author)
  • Pinto, M. (author)
  • El-Din, M. A. (author)
  • Compter, I. (author)
  • Holzner, B. (author)
  • Hofmeister, D. (author)
  • Chie, W. C. (author)
  • Harle, A. (author)
  • Flechtner, H. H. (author)
  • Bottomley, A. (author)
  • Eortc Quality Life Grp, Eortc Quality Life Grp (author)
  • Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar (creator_code:org_t)

Related titles

  • In:Psycho-Oncology: Wiley28, s. 1753-17611057-92491099-1611

Internet link

Find in a library

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view