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Coagulase-negative ...
Coagulase-negative staphylococcal prosthetic valve endocarditis--a contemporary update based on the International Collaboration on Endocarditis: prospective cohort study.
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Chu, V H (author)
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Miro, J M (author)
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Hoen, B (author)
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Cabell, C H (author)
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Pappas, P A (author)
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Jones, P (author)
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Stryjewski, M E (author)
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Anguera, I (author)
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Braun, S (author)
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Muñoz, P (author)
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Commerford, P (author)
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Tornos, P (author)
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Francis, J (author)
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Oyonarte, M (author)
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Selton-Suty, C (author)
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Morris, A J (author)
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Habib, G (author)
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Almirante, B (author)
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Sexton, D J (author)
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Corey, G R (author)
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Fowler, V G (author)
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- Olaison, Lars, 1949 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine
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(creator_code:org_t)
- 2008-12-18
- 2009
- English.
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In: Heart (British Cardiac Society). - : BMJ. - 1468-201X .- 1355-6037. ; 95:7, s. 570-6
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Abstract
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- To describe the contemporary features of coagulase-negative staphylococcal (CoNS) prosthetic valve endocarditis (PVE).Observational study of prospectively collected data from a multinational cohort of patients with infective endocarditis. Patients with CoNS PVE were compared to patients with Staphylococcus aureus and viridans streptococcal (VGS) PVE.The International Collaboration on Endocarditis-Prospective Cohort Study (ICE-PCS) is a contemporary cohort of patients with infective endocarditis from 61 centres in 28 countries.Adult patients in the ICE-PCS with definite PVE and no history of injecting drug use from June 2000 to August 2005 were included.None.Heart failure, intracardiac abscess, death.CoNS caused 16% (n = 86) of 537 cases of definite non-injecting drug use-associated PVE. Nearly one-half (n = 33/69, 48%) of patients with CoNS PVE presented between 60 days and 365 days of valve implantation. The rate of intracardiac abscess was significantly higher in patients with CoNS PVE (38%) than in patients with either S aureus (23%, p = 0.03) or VGS (20%, p = 0.05) PVE. The rate of abscess was particularly high in early (50%) and intermediate (52%) CoNS PVE. In-hospital mortality was 24% for CoNS PVE, 36% for S aureus PVE (p = 0.09) and 9.1% for VGS PVE (p = 0.08). Meticillin resistance was present in 68% of CoNS strains.Nearly one-half of CoNS PVE cases occur between 60 days and 365 days of prosthetic valve implantation. CoNS PVE is associated with a high rate of meticillin resistance and significant valvular complications.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Keyword
- Aged
- Bioprosthesis
- Coagulase
- Cross Infection
- drug therapy
- microbiology
- mortality
- Drug Resistance
- Microbial
- Endocarditis
- Bacterial
- drug therapy
- microbiology
- mortality
- Female
- Heart Valve Prosthesis
- Hospital Mortality
- Humans
- Male
- Middle Aged
- Postoperative Complications
- drug therapy
- microbiology
- mortality
- Prospective Studies
- Prosthesis-Related Infections
- drug therapy
- microbiology
- mortality
- Staphylococcal Infections
- drug therapy
- mortality
- Staphylococcus aureus
- Statistics
- Nonparametric
- Time Factors
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Chu, V H
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Miro, J M
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Hoen, B
-
Cabell, C H
-
Pappas, P A
-
Jones, P
-
show more...
-
Stryjewski, M E
-
Anguera, I
-
Braun, S
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Muñoz, P
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Commerford, P
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Tornos, P
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Francis, J
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Oyonarte, M
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Selton-Suty, C
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Morris, A J
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Habib, G
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Almirante, B
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Sexton, D J
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Corey, G R
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Fowler, V G
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Olaison, Lars, 1 ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Infectious Medic ...
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Heart (British C ...
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University of Gothenburg