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Free and hydrogel e...
Free and hydrogel encapsulated exosome-based therapies in regenerative medicine.
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Akbari, Ali (author)
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Jabbari, Nassrollah (author)
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Sharifi, Roholah (author)
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Ahmadi, Mahdi (author)
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Vahhabi, Ali (author)
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Seyedzadeh, Seyyed Javad (author)
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- Nawaz, Muhammad (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research
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Szafert, Sławomir (author)
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Mahmoodi, Monireh (author)
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Jabbari, Esmaiel (author)
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Asghari, Rahim (author)
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Rezaie, Jafar (author)
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(creator_code:org_t)
- Elsevier BV, 2020
- 2020
- English.
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In: Life sciences. - : Elsevier BV. - 1879-0631 .- 0024-3205. ; 249
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
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- Over the last few decades, mesenchymal stem cells-derived exosomes (MSCs-Ex) have attracted a lot of attention as a therapeutic tool in regenerative medicine. Exosomes are extracellular vehicles (EVs) that play important roles in cell-cell communication through various processes such as stress response, senescence, angiogenesis, and cell differentiation. Success in the field of regenerative medicine sparked exploration of the potential use of exosomes as key therapeutic effectors of MSCs to promote tissue regeneration. Various approaches including direct injection, intravenous injection, intraperitoneal injection, oral administration, and hydrogel-based encapsulation have been exploited to deliver exosomes to target tissues in different disease models. Despite significant advances in exosome therapy, it is unclear which approach is more effective for administering exosomes. Herein, we critically review the emerging progress in the applications of exosomes in the form of free or association with hydrogels as therapeutic agents for applications in regenerative medicine.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology (hsv//eng)
Keyword
- Exosomes
- Extracellular vesicles
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Akbari, Ali
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Jabbari, Nassrol ...
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Sharifi, Roholah
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Ahmadi, Mahdi
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Vahhabi, Ali
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Seyedzadeh, Seyy ...
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show more...
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Nawaz, Muhammad
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Szafert, Sławomi ...
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Mahmoodi, Monire ...
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Jabbari, Esmaiel
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Asghari, Rahim
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Rezaie, Jafar
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Medical Biotechn ...
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and Medical Biotechn ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Medical Biotechn ...
- Articles in the publication
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Life sciences
- By the university
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University of Gothenburg