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  • Basic, Carmen,1975Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden (author)

Young patients with heart failure: clinical characteristics and outcomes. Data from the Swedish Heart Failure, National Patient, Population and Cause of Death Registers

  • Article/chapterEnglish2020

Publisher, publication year, extent ...

  • 2020-08-03
  • Wiley,2020

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/295464
  • https://gup.ub.gu.se/publication/295464URI
  • https://doi.org/10.1002/ejhf.1952DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-168521URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:144290216URI

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  • Language:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Funding Agencies|Swedish Research CouncilSwedish Research Council [2013-5187 SIMSAM]; Swedish state [ALFGBG-433211, ALFGBG-725081, ALFGBG-717211]; Swedish Heart and Lung FoundationSwedish Heart-Lung Foundation [2013-0307, 2018-0419, 2015-0438]; Vastra Gotaland Region; Gothenburg Society of Medicine [GLS-328971]; Swedish Council for Health, Working Life and Welfare (FORTE) [2013-0325]; Cardiology Research Foundation at the Medical Clinic at Sahlgrenska University Hospital/Ostra; Swedish National Board of Health and Welfare; Swedish Association of Local Authorities and Regions; Swedish Society of Cardiology and Cardiology Research Foundation
  • Aims The prevalence and hospitalizations of patients with heart failure (HF) aged <55 years have increased in Sweden during the last decades. We aimed to compare characteristics of younger and older patients with HF, and examine survival in patients All patients >= 18 years in the Swedish Heart Failure Register from 2003 to 2014 were included. Data were merged with National Patient and Cause of Death Registers. Among 60 962 patients, 3752 (6.2%) were <55 years, and were compared with 7425 controls from the Population Register. Compared with patients >= 55 years, patients <55 years more frequently had registered diagnoses of obesity, dilated cardiomyopathy, congenital heart disease, and an ejection fraction <40% (9.8% vs. 4.7%, 27.2% vs. 5.5%, 3.7% vs. 0.8%, 67.9% vs. 45.1%, respectively; allP < 0.001). One-year all-cause mortality was 21.2%, 4.2%, and 0.3% in patients >= 55 years, patients <55 years, and controls <55 years, respectively (allP < 0.001). Patients <55 years had a five times higher mortality risk compared with controls [hazard ratio (HR) 5.48, 95% confidence interval (CI) 4.45-6.74]; the highest HR was in patients 18-34 years (HR 38.3, 95% CI 8.70-169; bothP < 0.001). At the age of 20, the estimated life-years lost was up to 36 years for 50% of patients, with declining estimates with increasing age. Conclusion Patients with HF <55 years had different comorbidities than patients >= 55 years. The highest mortality risk relative to that of controls was among the youngest patients.

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  • Rosengren, Annika,1951Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden(Swepub:gu)xrosan (author)
  • Alehagen, UrbanLinköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten(Swepub:liu)urbal84 (author)
  • Dahlström, Ulf,1946-Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US(Swepub:liu)ulfda85 (author)
  • Edner, M.Karolinska Institutet (author)
  • Fu, Michael,1963Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden(Swepub:gu)xfumiw (author)
  • Novak, Masuma,1969Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences,Univ Gothenburg, Sweden(Swepub:gu)xnovma (author)
  • Zverkova Sandström, TatianaGothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden(Swepub:gu)xzveta (author)
  • Schaufelberger, Maria,1954Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sweden(Swepub:gu)xscmar (author)
  • Göteborgs universitetInstitutionen för medicin, avdelningen för molekylär och klinisk medicin (creator_code:org_t)

Related titles

  • In:European Journal of Heart Failure: Wiley22:7, s. 1125-11321388-98421879-0844

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