Search: onr:"swepub:oai:gup.ub.gu.se/296173" > Temporal trends in ...
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000 | 06209naa a2200733 4500 | |
001 | oai:gup.ub.gu.se/296173 | |
003 | SwePub | |
008 | 240528s2020 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:liu-166185 | |
024 | 7 | a https://gup.ub.gu.se/publication/2961732 URI |
024 | 7 | a https://doi.org/10.1007/s00125-020-05152-12 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1661852 URI |
040 | a (SwePub)gud (SwePub)liu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Cherubini, V.u Salesi Hosp, Italy4 aut |
245 | 1 0 | a Temporal trends in diabetic ketoacidosis at diagnosis of paediatric type 1 diabetes between 2006 and 2016: results from 13 countries in three continents |
264 | c 2020-05-08 | |
264 | 1 | b Springer Science and Business Media LLC,c 2020 |
500 | a Funding Agencies|Projekt DEAL | |
520 | a Aims/hypothesis: The aim of this work was to evaluate geographical variability and trends in the prevalence of diabetic ketoacidosis (DKA), between 2006 and 2016, at the diagnosis of childhood-onset type 1 diabetes in 13 countries over three continents. Methods: An international retrospective study on DKA at diagnosis of diabetes was conducted. Data on age, sex, date of diabetes diagnosis, ethnic minority status and presence of DKA at diabetes onset were obtained from Australia, Austria, Czechia, Denmark, Germany, Italy, Luxembourg, New Zealand, Norway, Slovenia, Sweden, USA and the UK (Wales). Mean prevalence was estimated for the entire period, both overall and by country, adjusted for sex and age group. Temporal trends in annual prevalence of DKA were estimated using logistic regression analysis for each country, before and after adjustment for sex, age group and ethnic minority status. Results: During the study period, new-onset type 1 diabetes was diagnosed in 59,000 children (median age [interquartile range], 9.0years [5.5–11.7]; male sex, 52.9%). The overall adjusted DKA prevalence was 29.9%, with the lowest prevalence in Sweden and Denmark and the highest in Luxembourg and Italy. The adjusted DKA prevalence significantly increased over time in Australia, Germany and the USA while it decreased in Italy. Preschool children, adolescents and children from ethnic minority groups were at highest risk of DKA at diabetes diagnosis in most countries. A significantly higher risk was also found for females in Denmark, Germany and Slovenia. Conclusions/interpretation: DKA prevalence at type 1 diabetes diagnosis varied considerably across countries, albeit it was generally high and showed a slight increase between 2006 and 2016. Increased awareness of symptoms to prevent delay in diagnosis is warranted, especially in preschool children, adolescents and children from ethnic minority groups. © 2020, The Author(s). | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng |
653 | a Children with diabetes | |
653 | a Complications | |
653 | a Diabetic ketoacidosis | |
653 | a Diagnosis of diabetes | |
653 | a Epidemiology | |
653 | a Type 1 diabetes | |
653 | a Children with diabetes; Complications; Diabetic ketoacidosis; Diagnosis of diabetes; Epidemiology; Type 1 diabetes | |
700 | 1 | a Grimsmann, J. M.u Univ Ulm, Germany; German Ctr Diabet Res DZD, Germany4 aut |
700 | 1 | a Åkesson, Karinu Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Ryhov Cty Hosp, Sweden4 aut0 (Swepub:liu)karak14 |
700 | 1 | a Birkebæk, N. H.u Aarhus Univ Hosp, Denmark4 aut |
700 | 1 | a Cinek, O.u Charles Univ Prague, Czech Republic; Motol Univ Hosp, Czech Republic4 aut |
700 | 1 | a Dovč, K.u UMC Univ Childrens Hosp, Slovenia; Fac Med, Slovenia4 aut |
700 | 1 | a Gesuita, R.u Polytech Univ Marche, Italy4 aut |
700 | 1 | a Gregory, J. W.u Cardiff Univ, Wales4 aut |
700 | 1 | a Hanås, Ragnar,d 1951u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,NU Hosp Grp, Sweden; Gothenburg Univ, Sweden4 aut0 (Swepub:gu)xhanra |
700 | 1 | a Hofer, S. E.u Med Univ Innsbruck, Austria4 aut |
700 | 1 | a Holl, R. W.u Univ Ulm, Germany; German Ctr Diabet Res DZD, Germany4 aut |
700 | 1 | a Jefferies, C.u Starship Childrens Hlth, New Zealand4 aut |
700 | 1 | a Joner, G.u Oslo Univ Hosp, Norway; Univ Oslo, Norway4 aut |
700 | 1 | a King, B. R.u Univ Newcastle, Australia4 aut |
700 | 1 | a Mayer-Davis, E. J.u Univ N Carolina, NC 27515 USA4 aut |
700 | 1 | a Peña, A. S.u Univ Adelaide, Australia4 aut |
700 | 1 | a Rami-Merhar, B.u Med Univ Vienna, Austria4 aut |
700 | 1 | a Schierloh, U.u Ctr Hosp, Luxembourg4 aut |
700 | 1 | a Skrivarhaug, T.u Oslo Univ Hosp, Norway; Univ Oslo, Norway4 aut |
700 | 1 | a Sumnik, Z.u Charles Univ Prague, Czech Republic; Motol Univ Hosp, Czech Republic4 aut |
700 | 1 | a Svensson, J.u Copenhagen Univ Hosp, Denmark4 aut |
700 | 1 | a Warner, J. T.u Univ Hosp Wales, Wales4 aut |
700 | 1 | a Bratina, N.u UMC Univ Childrens Hosp, Slovenia; Fac Med, Slovenia4 aut |
700 | 1 | a Dabelea, D.u Univ Colorado, CO USA4 aut |
710 | 2 | a Salesi Hosp, Italyb Univ Ulm, Germany; German Ctr Diabet Res DZD, Germany4 org |
773 | 0 | t Diabetologiad : Springer Science and Business Media LLCg 63, s. 1530-1541q 63<1530-1541x 0012-186Xx 1432-0428 |
856 | 4 | u https://link.springer.com/content/pdf/10.1007/s00125-020-05152-1.pdf |
856 | 4 | u https://liu.diva-portal.org/smash/get/diva2:1437701/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://gup.ub.gu.se/publication/296173 |
856 | 4 8 | u https://doi.org/10.1007/s00125-020-05152-1 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-166185 |
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