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The Prospective Stu...
The Prospective Studies of Atherosclerosis (Proof-ATHERO) Consortium: Design and Rationale
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- Tschiderer, L. (author)
- Med Univ Innsbruck, Dept Neurol, Anichstr 35, AT-6020 Innsbruck, Austria.
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- Seekircher, L. (author)
- Med Univ Innsbruck, Dept Neurol, Anichstr 35, AT-6020 Innsbruck, Austria.
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- Klingenschmid, G. (author)
- Med Univ Innsbruck, Dept Neurol, Anichstr 35, AT-6020 Innsbruck, Austria.
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show more...
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- Izzo, R. (author)
- Univ Naples Federico II, Dept Adv Biochem Sci, Naples, Italy.
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- Baldassarre, D. (author)
- Univ Milan, Dept Med Biotechnol & Translat Med, Milan, Italy.;Ctr Cardiol Monzino IRCCS, Milan, Italy.
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- Iglseder, B. (author)
- Gemeinnutzige Salzburger Landeskliniken Betriebsg, Dept Geriatr Med, Salzburg, Austria.;Paracelsus Med Univ, Dept Geriatr Med, Salzburg, Austria.
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- Calabresi, L. (author)
- Univ Milan, Dept Pharmacol & Biomol Sci, Milan, Italy.
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- Liu, J. (author)
- Capital Med Univ, Beijing Anzhen Hosp, Dept Epidemiol, Beijing, Peoples R China.
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- Price, J. (author)
- Univ Edinburgh, Usher Inst, Edinburgh, Midlothian, Scotland.
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- Bae, J. H. (author)
- Konyang Univ Hosp, Ctr Heart, Daejeon, South Korea.;Konyang Univ, Dept Cardiol, Coll Med, Daejeon, South Korea.,Showa Univ, Sch Med, Dept Med, Div Nephrol, Tokyo, Japan.
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- Brouwers, F. (author)
- Haga Teaching Hosp, Dept Cardiol, The Hague, Netherlands.
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- de Groot, E. (author)
- Imagelabonline & Cardiovasc, Eindhoven, Netherlands.
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- Schmidt, Caroline, 1966 (author)
- Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory,Univ Gothenburg, Wallenberg Lab Cardiovasc Res, Gothenburg, Sweden.
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- Bergström, Göran, 1964 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Mol & Clin Med, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Reg Vastra Gotaland, Dept Clin Physiol, Gothenburg, Sweden.
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- Asci, G. (author)
- Ege Univ, Sch Med, Dept Nephrol, Bornova, Turkey.
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- Gresele, P. (author)
- Univ Perugia, Div Internal & Cardiovasc Med, Dept Med, Perugia, Italy.;Hamamatsu Univ Hosp, Blood Purificat Unit, Hamamatsu, Shizuoka, Japan.
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- Okazaki, S. (author)
- Osaka Univ, Grad Sch Med, Dept Neurol, Osaka, Japan.
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- Kapellas, K. (author)
- Univ Adelaide, Australian Res Ctr Populat Oral Hlth, Adelaide, SA, Australia.
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- Landecho, M. (author)
- Univ Clin Navarra, Dept Internal Med, Navarra, Spain.,Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands.
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- Sattar, N. (author)
- Univ Glasgow, BHF Glasgow Cardiovasc Res Ctr, Glasgow, Lanark, Scotland.
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- Agewall, S. (author)
- Karolinska Institutet
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- Zou, Z. Y. (author)
- Peking Univ, Inst Child & Adolescent Hlth, Sch Publ Hlth, Beijing, Peoples R China.
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- Byrne, C. D. (author)
- Univ Southampton, Southampton Gen Hosp, Inst Dev Sci, Human Dev & Hlth Acad Unit,Fac Med, Southampton, Hants, England.
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- Nanayakkara, P. W. B. (author)
- Amsterdam UMC, Dept Clin Neurophysiol, Amsterdam, Netherlands.,Med Univ Innsbruck, Dept Neurol, Anichstr 35, AT-6020 Innsbruck, Austria.;Univ Cambridge, Dept Publ Hlth & Primary Care, Cambridge, England.
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- Papagianni, A. (author)
- Hippokrateion Hosp, Univ Dept Nephrol, Thessaloniki, Greece.
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- Witham, M. D. (author)
- Newcastle Univ, NIHR Newcastle Biomed Res Ctr, AGE Res Grp, Newcastle, England.;Newcastle Upon Tyne Hosp Trust, Newcastle, England.,Monash Univ, Alfred Hosp, Dept Epidemiol & Prevent Med, Melbourne, Vic, Australia.
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- Bernal, E. (author)
- Reina Sofia Hosp, Infect Dis Unit, Murcia, Spain.
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- Ekart, R. (author)
- Univ Med Ctr Maribor, Dept Dialysis, Maribor, Slovenia.
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- van Agtmael, M. A. (author)
- Vrije Univ, Amsterdam UMC, Dept Internal Med, Amsterdam, Netherlands.
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- Neves, M. F. (author)
- Univ Estado Rio De Janeiro, Dept Clin Med, Rio De Janeiro, Brazil.
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- Sato, E. (author)
- Shinmatsudo Cent Gen Hosp, Div Nephrol, Chiba, Japan.
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- Ezhov, M. (author)
- Natl Med Res Ctr Cardiol, Lab Lipid Disorders, Moscow, Russia.
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- Walters, M. (author)
- Univ Glasgow, Sch Med Dent & Nursing, Glasgow, Lanark, Scotland.,Goethe Univ, Dept Neurol, Frankfurt, Germany.
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- Olsen, M. H. (author)
- Univ Southern Denmark, Holbaek Hosp, Dept Internal Med, Odense, Denmark.,Tech Univ Dresden, Ctr Clin Studies, Dresden, Germany.
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- Stolic, R. (author)
- Univ Kragujevac, Dept Internal Med, Fac Med Sci, Kragujevac, Serbia.
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- Zozulinska-Ziolkiewicz, D. (author)
- Poznan Univ Med Sci, Dept Internal Med & Diabetol, Poznan, Poland.
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Hanefeld, M. (author)
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- Staub, D. (author)
- Univ Basel Hosp, Dept Angiol, Basel, Switzerland.
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- Nagai, M. (author)
- Hiroshima City Asa Hosp, Dept Internal Med Gen Med & Cardiol, Hiroshima, Japan.
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- Nieuwkerk, P. T. (author)
- Amsterdam UMC, Locat AMC, Dept Med Psychol, Amsterdam, Netherlands.
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- Huisman, M. V. (author)
- Leiden Univ, Med Ctr, Dept Thrombosis & Hemostasis, Leiden, Netherlands.
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- Kato, A. (author)
- Univ Perugia, Div Internal & Cardiovasc Med, Dept Med, Perugia, Italy.
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Honda, H. (author)
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- Parraga, G. (author)
- Western Univ, Dept Med Biophys, London, ON, Canada.
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Magliano, D. (author)
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- Gabriel, R. (author)
- Inst Salud Carlos III, Natl Sch Publ Hlth, Madrid, Spain.
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- Rundek, T. (author)
- Univ Miami, Miller Sch Med, Dept Neurol, Miami, FL 33136 USA.
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- Espeland, M. A. (author)
- Wake Forest Sch Med, Dept Biostat Sci, Winston Salem, NC 27101 USA.
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- Kiechl, S. (author)
- Med Univ Innsbruck, Dept Neurol, Anichstr 35, AT-6020 Innsbruck, Austria.;VASCage GmbH, Res Ctr Vasc Ageing & Stroke, Innsbruck, Austria.
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- Willeit, J. (author)
- Med Univ Innsbruck, Dept Neurol, Anichstr 35, AT-6020 Innsbruck, Austria.,Amsterdam UMC, Locat Vumc, Dept Epidemiol & Biostat, Amsterdam, Netherlands.
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- Lind, Lars (author)
- Uppsala universitet,Klinisk epidemiologi
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- Jean, P. (author)
- Univ Paris 05, Paris Cardiovasc Res Ctr PARCC, Paris, France.
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- Lonn, E. (author)
- McMaster Univ, Dept Med & Populat Hlth Res Inst, Hamilton, ON, Canada.;Hamilton Gen Hosp, Hamilton, ON, Canada.
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- Tuomainen, T. P. (author)
- Univ Eastern Finland, Inst Publ Hlth & Clin Nutr, Kuopio Campus, Kuopio, Finland.
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- Catapano, A. (author)
- Univ Milan, Dept Pharmacol & Biomol Sci, Milan, Italy.;IRCCS Multimed, Milan, Italy.
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- Chien, K. L. (author)
- Natl Taiwan Univ, Inst Epidemiol & Prevent Med, Taipei, Taiwan.
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- Sander, D. (author)
- Benedictus Hosp Tutzing & Feldafing, Dept Neurol, Feldafing, Germany.;Tech Univ Munich, Dept Neurol, Munich, Germany.
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- Kavousi, M. (author)
- Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands.
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Beulens, J. W. J. (author)
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Bots, M. L. (author)
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- Sweeting, M. J. (author)
- Univ Leicester, Dept Hlth Sci, Leicester, Leics, England.
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Lorenz, M. W. (author)
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Willeit, P. (author)
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Med Univ Innsbruck, Dept Neurol, Anichstr 35, AT-6020 Innsbruck, Austria Univ Naples Federico II, Dept Adv Biochem Sci, Naples, Italy. (creator_code:org_t)
- 2020-07-01
- 2020
- English.
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In: Gerontology. - : S. Karger AG. - 0304-324X .- 1423-0003. ; 66:5, s. 447-459
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Abstract
Subject headings
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- Atherosclerosis - the pathophysiological mechanism shared by most cardiovascular diseases - can be directly or indirectly assessed by a variety of clinical tests including measurement of carotid intima-media thickness, carotid plaque, ankle-brachial index, pulse wave velocity, and coronary artery calcium. The Prospective Studies of Atherosclerosis (Proof-ATHERO) consortium (https://clinicalepi.i-med.ac.at/research/proof-athero/) collates de-identified individual-participant data of studies with information on atherosclerosis measures, risk factors for cardiovascular disease, and incidence of cardiovascular diseases. It currently comprises 74 studies that involve 106,846 participants from 25 countries and over 40 cities. In summary, 21 studies recruited participants from the general population (n = 67,784), 16 from high-risk populations (n = 22,677), and 37 as part of clinical trials (n = 16,385). Baseline years of contributing studies range from April 1980 to July 2014; the latest follow-up was until June 2019. Mean age at baseline was 59 years (standard deviation: 10) and 50% were female. Over a total of 830,619 person-years of follow-up, 17,270 incident cardiovascular events (including coronary heart disease and stroke) and 13,270 deaths were recorded, corresponding to cumulative incidences of 2.1% and 1.6% per annum, respectively. The consortium is coordinated by the Clinical Epidemiology Team at the Medical University of Innsbruck, Austria. Contributing studies undergo a detailed data cleaning and harmonisation procedure before being incorporated in the Proof-ATHERO central database. Statistical analyses are being conducted according to pre-defined analysis plans and use established methods for individual-participant data meta-analysis. Capitalising on its large sample size, the multi-institutional collaborative Proof-ATHERO consortium aims to better characterise, understand, and predict the development of atherosclerosis and its clinical consequences. (c) 2020 S. Karger AG, Basel
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Keyword
- Prospective studies
- Consortium
- Individual-participant data
- Atherosclerosis
- Repeat measurements
- Cardiovascular disease
- intima-media thickness
- cardiovascular risk-factors
- individual
- participant data
- common carotid-artery
- myocardial-infarction
- natural
- course
- vascular risk
- calcium score
- disease
- metaanalysis
- Geriatrics & Gerontology
- Prospective studies
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Tschiderer, L.
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Seekircher, L.
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Klingenschmid, G ...
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Izzo, R.
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Baldassarre, D.
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Iglseder, B.
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show more...
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Calabresi, L.
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Liu, J.
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Price, J.
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Bae, J. H.
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Brouwers, F.
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de Groot, E.
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Schmidt, Carolin ...
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Bergström, Göran ...
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Asci, G.
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Gresele, P.
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Okazaki, S.
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Kapellas, K.
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Landecho, M.
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Sattar, N.
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Agewall, S.
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Zou, Z. Y.
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Byrne, C. D.
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Nanayakkara, P. ...
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Papagianni, A.
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Witham, M. D.
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Bernal, E.
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Ekart, R.
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van Agtmael, M. ...
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Neves, M. F.
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Sato, E.
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Ezhov, M.
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Walters, M.
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Olsen, M. H.
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Stolic, R.
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Zozulinska-Ziolk ...
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Hanefeld, M.
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Staub, D.
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Nagai, M.
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Nieuwkerk, P. T.
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Huisman, M. V.
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Kato, A.
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Honda, H.
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Parraga, G.
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Magliano, D.
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Gabriel, R.
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Rundek, T.
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Espeland, M. A.
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Kiechl, S.
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Willeit, J.
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Lind, Lars
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Jean, P.
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Lonn, E.
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Tuomainen, T. P.
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Catapano, A.
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Chien, K. L.
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Sander, D.
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Kavousi, M.
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Beulens, J. W. J ...
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Bots, M. L.
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Sweeting, M. J.
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Lorenz, M. W.
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Willeit, P.
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
- Articles in the publication
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Gerontology
- By the university
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University of Gothenburg
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Uppsala University
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Karolinska Institutet