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ESMO consensus conference recommendations on the management of locoregional melanoma: under the auspices of the ESMO Guidelines Committee

Michielin, O. (author)
van Akkooi, A. (author)
Lorigan, P. (author)
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Ascierto, P. A. (author)
Dummer, R. (author)
Robert, C. (author)
Arance, A. (author)
Blank, C. U. (author)
Sileni, V. C. (author)
Donia, M. (author)
Faries, M. B. (author)
Gaudy-Marqueste, C. (author)
Gogas, H. (author)
Grob, J. J. (author)
Guckenberger, M. (author)
Haanen, J. (author)
Hayes, A. J. (author)
Hoeller, C. (author)
Lebbe, C. (author)
Lugowska, I. (author)
Mandala, M. (author)
Marquez-Rodas, I. (author)
Nathan, P. (author)
Neyns, B. (author)
Olofsson Bagge, Roger, 1978 (author)
Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
Puig, S. (author)
Rutkowski, P. (author)
Schilling, B. (author)
Sondak, V. K. (author)
Tawbi, H. (author)
Testori, A. (author)
Keilholz, U. (author)
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 (creator_code:org_t)
Elsevier BV, 2020
2020
English.
In: Annals of Oncology. - : Elsevier BV. - 0923-7534. ; 31:11, s. 1449-1461
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The European Society for Medical Oncology (ESMO) held a consensus conference on melanoma on 5-7 September 2019 in Amsterdam, The Netherlands. The conference included a multidisciplinary panel of 32 leading experts in the management of melanoma. The aim of the conference was to develop recommendations on topics that are not covered in detail in the current ESMO Clinical Practice Guideline and where available evidence is either limited or conflicting. The main topics identified for discussion were: (i) the management of locoregional disease; (ii) targeted versus immunotherapies in the adjuvant setting; (iii) targeted versus immunotherapies for the first-line treatment of metastatic melanoma; (iv) when to stop immunotherapy or targeted therapy in the metastatic setting; and (v) systemic versus local treatment of brain metastases. The expert panel was divided into five working groups in order to each address questions relating to one of the five topics outlined above. Relevant scientific literature was reviewed in advance. Recommendations were developed by the working groups and then presented to the entire panel for further discussion and amendment before voting. This manuscript presents the results relating to the management of locoregional melanoma, including findings from the expert panel discussions, consensus recommendations and a summary of evidence supporting each recommendation. All participants approved the final manuscript.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Keyword

melanoma
consensus
treatment
immunotherapy
targeted therapy
adjuvant
lymph-node biopsy
stage-iii melanoma
american joint committee
isolated limb perfusion
sentinel-node
high-risk
adjuvant dabrafenib
cutaneous melanoma
malignant-melanoma
adverse events
Oncology

Publication and Content Type

ref (subject category)
art (subject category)

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