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Low adherence to CK...
Low adherence to CKD-specific dietary recommendations associates with impaired kidney function, dyslipidemia, and inflammation
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Kaesler, N. (author)
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- Baid-Agrawal, Seema, 1966 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine
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Grams, S. (author)
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Nadal, J. (author)
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Schmid, M. (author)
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Schneider, M. P. (author)
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Eckardt, K. U. (author)
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Floege, J. (author)
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Bergmann, M. M. (author)
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Schlieper, G. (author)
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Saritas, T. (author)
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(creator_code:org_t)
- 2021-02-02
- 2021
- English.
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In: European Journal of Clinical Nutrition. - : Springer Science and Business Media LLC. - 0954-3007 .- 1476-5640. ; 75, s. 1389-1397
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https://www.nature.c...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
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- Background/Objectives A diet following chronic kidney disease (CKD)-specific recommendations is considered essential for optimal management of patients with CKD. However, data on the adherence to these recommendations and its implications for health-relevant biomarkers are lacking. The objectives were to estimate adherence to CKD-specific dietary recommendations, to identify characteristics and lifestyle variables associated with poor adherence, and to investigate the relationship of adherence with biomarkers. Methods In this cross-sectional analysis, average dietary intake was estimated in 3193 participants with moderately severe CKD enrolled into the observational multicenter German CKD study using a food frequency questionnaire. A CKD diet score was developed to assess adherence to CKD-specific dietary recommendations based on intake of sodium, potassium, fiber, protein, sugar, and cholesterol. The associations of dietary adherence with characteristics, lifestyle variables, and biomarker levels were determined. Results Logistic regression analysis revealed younger age, higher body mass index, male gender, lower educational attainment, various lifestyle variables (cigarette smoking, infrequent alcohol consumption, low physical activity), and lower estimated glomerular filtrate rate associated with lower adherence to dietary recommendations. Low adherence to dietary recommendations was further associated with dyslipidemia, higher uric acid, and C-reactive protein levels. Associations between low dietary adherence and biomarkers were mostly driven by low intake of fiber and potassium, and high intake of sugar and cholesterol. Conclusions This study revealed differential characteristics and biomarkers associated with lower adherence to CKD-specific dietary recommendations. Promotion of CKD-specific dietary recommendations may help to mitigate the adverse prognosis in CKD patients.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Keyword
- Nutrition & Dietetics
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Kaesler, N.
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Baid-Agrawal, Se ...
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Grams, S.
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Nadal, J.
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Schmid, M.
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Schneider, M. P.
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show more...
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Eckardt, K. U.
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Floege, J.
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Bergmann, M. M.
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Schlieper, G.
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Saritas, T.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Nutrition and Di ...
- Articles in the publication
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European Journal ...
- By the university
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University of Gothenburg