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Overview of CAPICE-Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe-an EU Marie Sklodowska-Curie International Training Network

Rajula, H. S. R. (author)
Manchia, M. (author)
Karolinska Institutet
Agarwal, K. (author)
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Akingbuwa, W. A. (author)
Allegrini, A. G. (author)
Diemer, E. (author)
Doering, Sabrina (author)
Gothenburg University,Göteborgs universitet,Centrum för etik, juridik och mental hälsa,Gillbergcentrum,Centre for Ethics, Law, and Mental Health,Gillberg Neuropsychiatry Centre
Haan, E. (author)
Jami, E. S. (author)
Karhunen, V. (author)
Leone, M. (author)
Schellhas, L. (author)
Thompson, A. (author)
Karolinska Institutet
van den Berg, S. M. (author)
Bergen, S. E. (author)
Karolinska Institutet
Hammerschlag, A. R. (author)
Jarvelin, M. R. (author)
Leval, A. (author)
Lichtenstein, P. (author)
Karolinska Institutet
Lundstrom, S. (author)
Mauri, M. (author)
Munafo, M. R. (author)
Myers, D. (author)
Plomin, R. (author)
Rimfeld, K. (author)
Karolinska Institutet
Tiemeier, H. (author)
Ystrom, E. (author)
Fanos, V. (author)
Bartels, M. (author)
Middeldorp, C. M. (author)
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 (creator_code:org_t)
2021-01-20
2022
English.
In: European Child & Adolescent Psychiatry. - : Springer Science and Business Media LLC. - 1018-8827 .- 1435-165X. ; 31:5, s. 829-839
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER) identified child and adolescent mental illness as a priority area for research. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) is a European Union (EU) funded training network aimed at investigating the causes of individual differences in common childhood and adolescent psychopathology, especially depression, anxiety, and attention deficit hyperactivity disorder. CAPICE brings together eight birth and childhood cohorts as well as other cohorts from the EArly Genetics and Life course Epidemiology (EAGLE) consortium, including twin cohorts, with unique longitudinal data on environmental exposures and mental health problems, and genetic data on participants. Here we describe the objectives, summarize the methodological approaches and initial results, and present the dissemination strategy of the CAPICE network. Besides identifying genetic and epigenetic variants associated with these phenotypes, analyses have been performed to shed light on the role of genetic factors and the interplay with the environment in influencing the persistence of symptoms across the lifespan. Data harmonization and building an advanced data catalogue are also part of the work plan. Findings will be disseminated to non-academic parties, in close collaboration with the Global Alliance of Mental Illness Advocacy Networks-Europe (GAMIAN-Europe).

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)

Keyword

Childhood and adolescence psychopathology
Depression
Anxiety
Attention deficit hyperactivity disorder (ADHD)
Psychiatric genetics
Psychology
Pediatrics
Psychiatry

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art (subject category)

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