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PROVE-Pre-Eclampsia...
PROVE-Pre-Eclampsia Obstetric Adverse Events: Establishment of a Biobank and Database for Pre-Eclampsia
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- Bergman, Lina, 1982 (author)
- Uppsala universitet,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology,Klinisk obstetrik,Univ Gothenburg, Sahlgrenska Acad, Inst Clin Sci, Dept Obstet & Gynaecol, S-41650 Gothenburg, Sweden.;Stellenbosch Univ, Dept Obstet & Gynaecol, Fac Med & Hlth Sci, ZA-7505 Cape Town, South Africa.
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- Bergman, Karl (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Mol & Clin Med, S-41650 Gothenburg, Sweden.
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- Langenegger, E. (author)
- Stellenbosch Univ, Dept Obstet & Gynaecol, Fac Med & Hlth Sci, ZA-7505 Cape Town, South Africa.
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- Moodley, A. (author)
- Stellenbosch Univ, Dept Obstet & Gynaecol, Fac Med & Hlth Sci, ZA-7505 Cape Town, South Africa.
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- Griffith-Richards, S. (author)
- Stellenbosch Univ, Div Radiodiag, Dept Med Imaging & Clin Oncol, Fac Med & Hlth Sci, ZA-7505 Cape Town, South Africa.,Stellenbosch Univ, Dept Obstet & Gynaecol, Fac Med & Hlth Sci, ZA-7505 Cape Town, South Africa.
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- Wikström, Johan, 1964- (author)
- Uppsala universitet,Radiologi
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- Hall, D. (author)
- Stellenbosch Univ, Dept Obstet & Gynaecol, Fac Med & Hlth Sci, ZA-7505 Cape Town, South Africa.
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- Joubert, L. (author)
- Stellenbosch Univ, Div Cardiol, Dept Med Med & Hlth Sci, ZA-7505 Cape Town, South Africa.
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- Herbst, P. (author)
- Univ Med Ctr Groningen, Dept Obstet & Gynaecol, NL-9713 Groningen, Netherlands.
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Schell, S. (author)
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- van Veen, T. (author)
- Univ Med Ctr Groningen, Dept Obstet & Gynaecol, NL-9713 Groningen, Netherlands.
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- Belfort, M. (author)
- Baylor Coll Med, Dept Obstet & Gynaecol, Houston, TX 77004 USA.
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- Tong, S. Y. C. (author)
- Univ Melbourne, Translat Obstet Grp, Dept Obstet & Gynaecol, Parkville, Vic 3010, Australia.;Mercy Hosp Women, Mercy Perinatal, Heidelberg, Vic 3010, Australia.,Stellenbosch Univ, Dept Obstet & Gynaecol, Fac Med & Hlth Sci, ZA-7505 Cape Town, South Africa.;Univ Melbourne, Translat Obstet Grp, Dept Obstet & Gynaecol, Parkville, Vic 3010, Australia.
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- Walker, S. (author)
- Univ Melbourne, Translat Obstet Grp, Dept Obstet & Gynaecol, Parkville, Vic 3010, Australia.;Mercy Hosp Women, Mercy Perinatal, Heidelberg, Vic 3010, Australia.
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- Hastie, R. (author)
- Univ Melbourne, Translat Obstet Grp, Dept Obstet & Gynaecol, Parkville, Vic 3010, Australia.;Mercy Hosp Women, Mercy Perinatal, Heidelberg, Vic 3010, Australia.
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Cluver, C. (author)
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(creator_code:org_t)
- 2021-04-20
- 2021
- English.
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In: Cells. - : MDPI AG. - 2073-4409. ; 10:4
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https://doi.org/10.3...
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https://uu.diva-port... (primary) (Raw object)
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https://gup.ub.gu.se...
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https://doi.org/10.3...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- Pre-eclampsia is a leading cause of maternal and perinatal morbidity and mortality. The burden of disease lies mainly in low-middle income countries. The aim of this project is to establish a pre-eclampsia biobank in South Africa to facilitate research in the field of pre-eclampsia with a focus on phenotyping severe disease.The approach of our biobank is to collect biological specimens, detailed clinical data, tests, and biophysical examinations, including magnetic resonance imaging (MRI) of the brain, MRI of the heart, transcranial Doppler, echocardiography, and cognitive function tests.Women diagnosed with pre-eclampsia and normotensive controls are enrolled in the biobank at admission to Tygerberg University Hospital (Cape Town, South Africa). Biological samples and clinical data are collected at inclusion/delivery and during the hospital stay. Special investigations as per above are performed in a subset of women. After two months, women are followed up by telephonic interviews. This project aims to establish a biobank and database for severe organ complications of pre-eclampsia in a low-middle income country where the incidence of pre-eclampsia with organ complications is high. The study integrates different methods to investigate pre-eclampsia, focusing on improved understanding of pathophysiology, prediction of organ complications, and potentially future drug evaluation and discovery.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
Keyword
- pre-eclampsia
- eclampsia
- pulmonary oedema
- biobank
- database
- Cell Biology
- pre-eclampsia
Publication and Content Type
- ref (subject category)
- art (subject category)
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Cells
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Bergman, Lina, 1 ...
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Bergman, Karl
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Langenegger, E.
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Moodley, A.
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Griffith-Richard ...
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Wikström, Johan, ...
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show more...
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Hall, D.
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Joubert, L.
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Herbst, P.
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Schell, S.
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van Veen, T.
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Belfort, M.
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Tong, S. Y. C.
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Walker, S.
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Hastie, R.
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Cluver, C.
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Cells
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University of Gothenburg
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Uppsala University