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Marked point proces...
Marked point process analysis of epidermal nerve fibres
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- Ghorbanpour, F. (author)
- Allameh Tabatabai University
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- Särkkä, Aila, 1962 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för matematiska vetenskaper,Department of Mathematical Sciences,Chalmers tekniska högskola,Chalmers University of Technology,University of Gothenburg
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- Pourtaheri, R. (author)
- Allameh Tabatabai University
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(creator_code:org_t)
- 2021-04-17
- 2021
- English.
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In: Journal of Microscopy. - : Wiley. - 0022-2720 .- 1365-2818. ; 283:1, s. 41-50
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Abstract
Subject headings
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- Epidermal nerve fibre (ENF) density and summed length of ENFs per epidermal surface area are reduced, and ENFs may appear more clustered within the epidermis in subjects suffering from diabetic neuropathy compared to healthy subjects. Therefore, it is important to understand the spatial behaviour of ENFs in healthy and neuropathy subjects. By using confocal microscopy data , we study the spatial structure of epidermal nerves by regarding the nerve tree locations as realizations of marked point processes . The termination points of the fibres of a nerve tree are used to define a reactive territory which is taken as a mark for the nerve tree location. We study the differences in the spatial pattern of ENFs between healthy subjects and subjects suffering from mild diabetic neuropathy by using Ripley's K function and the mark correlation function. In addition, we propose a marked sequential point process model for the nerve tree locations. Data are replicated point patterns, where we have several patterns from each subject and from each group.
Subject headings
- NATURVETENSKAP -- Matematik (hsv//swe)
- NATURAL SCIENCES -- Mathematics (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Industriell bioteknik -- Bioteknisk apparatteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Industrial Biotechnology -- Bioengineering Equipment (hsv//eng)
- NATURVETENSKAP -- Data- och informationsvetenskap -- Bioinformatik (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences -- Bioinformatics (hsv//eng)
- NATURVETENSKAP -- Geovetenskap och miljövetenskap -- Naturgeografi (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences -- Physical Geography (hsv//eng)
Keyword
- coverage
- mark correlation
- marked sequential point process
- reactive
- territory
- replicates
- Microscopy
- coverage
Publication and Content Type
- ref (subject category)
- art (subject category)
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