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The Genomic HyperBrowser: Inferential genomics at the sequence level

Sandve, Geir K. (author)
Gundersen, Sveinung (author)
Rydbeck, Halfdan, 1972 (author)
Gothenburg University,Göteborgs universitet,Core Facilities, Bioinformatics,Institutionen för neurovetenskap och fysiologi,Core Facilities, Bioinformatics,Institute of Neuroscience and Physiology
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Glad, Ingrid K. (author)
Holden, Lars (author)
Holden, Marit (author)
Liestøl, Knut (author)
Clancy, Trevor (author)
Ferkingstad, Egil (author)
Johansen, Morten (author)
Nygaard, Vegard (author)
Tøstesen, Eivind (author)
Frigessi, Arnoldo (author)
Hovig, Eivind (author)
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 (creator_code:org_t)
Springer Science and Business Media LLC, 2010
2010
English.
In: Genome Biology. - : Springer Science and Business Media LLC. - 1474-7596 .- 1474-760X .- 1465-6906. ; 11
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The immense increase in the generation of genomic scale data poses an unmet analytical challenge, due to a lack of established methodology with the required flexibility and power. We propose a first principled approach to statistical analysis of sequence-level genomic information. We provide a growing collection of generic biological investigations that query pairwise relations between tracks, represented as mathematical objects, along the genome. The Genomic HyperBrowser implements the approach and is available at http://hyperbrowser.uio.no.© 2010 Sandve et al.; licensee BioMed Central Ltd.

Subject headings

NATURVETENSKAP  -- Biologi -- Bioinformatik och systembiologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Bioinformatics and Systems Biology (hsv//eng)

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