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Excessive Daytime Sleepiness in Obstructive Sleep Apnea Patients Treated With Continuous Positive Airway Pressure: Data From the European Sleep Apnea Database

Bonsignore, M. R. (author)
Pepin, J. L. (author)
Cibella, F. (author)
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Barbera, C. D. (author)
Marrone, O. (author)
Verbraecken, J. (author)
Saaresranta, T. (author)
Basoglu, O. K. (author)
Trakada, G. (author)
Bouloukaki, I. (author)
McNicholas, W. T. (author)
Bailly, S. (author)
Pataka, A. (author)
Kvamme, J. A. (author)
Hein, H. (author)
Mihaicuta, S. (author)
Grote, Ludger, 1964 (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine
Fanfulla, F. (author)
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 (creator_code:org_t)
2021-08-09
2021
English.
In: Frontiers in Neurology. - : Frontiers Media SA. - 1664-2295. ; 12
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • follow-up visit after 4 months to 2 years. The change in ESS (n = 2,190) was weakly correlated with CPAP use (R2 = 0.023, p 0.0001). Logistic regression showed that an ESS score 10 at the first follow-up visit was associated directly with ESS at baseline and inversely with duration of follow-up, and CPAP use (R2 of the model: 0.417). EDS showed heterogeneity in different European countries both at baseline and at the first follow-up visit, suggesting modulation by cultural and lifestyle factors. In conclusion, residual EDS in CPAP-treated OSA occurred in approximately one in four patients at follow-up; its prevalence was highest (40%) in the first 3 months of treatment and subsequently decreased. The finding of residual EDS in a significant percentage of optimally treated OSA patients suggests that wake-promoting agents may be useful, but their indication should be evaluated after at least 3 months of treatment.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Keyword

residual sleepness
CPAP adherence
follow-up
Epworth sleepness Scale
sleep duration
sleep latency
wake-active neurons
residual sleepiness
important difference
cpap
use
obesity
scale
Neurosciences & Neurology

Publication and Content Type

ref (subject category)
art (subject category)

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