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Sex differences in ...
Sex differences in dementia and response to a lifestyle intervention: Evidence from Nordic population-based studies and a prevention trial
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- Sindi, S. (author)
- Karolinska Institutet
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- Kåreholt, Ingemar (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Jönköping University, Sweden,HHJ, Institutet för gerontologi,HHJ. ARN-J (Aging Research Network - Jönköping)
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- Ngandu, T. (author)
- Karolinska Institutet
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- Rosenberg, A. (author)
- Univ Eastern Finland, Inst Publ Hlth & Clin Nutr, Kuopio, Finland
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- Kulmala, J. (author)
- Karolinska Institutet
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- Johansson, Lena, 1972 (author)
- Gothenburg University,Göteborgs universitet,Centrum för åldrande och hälsa (AgeCap),Institutionen för neurovetenskap och fysiologi,Centre for Ageing and Health (Agecap),Institute of Neuroscience and Physiology,Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Ctr Hlth & Ageing AGECAP, Gothenburg, Sweden
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- Wetterberg, Hanna (author)
- Gothenburg University,Göteborgs universitet,Centrum för åldrande och hälsa (AgeCap),Institutionen för neurovetenskap och fysiologi,Centre for Ageing and Health (Agecap),Institute of Neuroscience and Physiology,Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Ctr Hlth & Ageing AGECAP, Gothenburg, Sweden
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- Skoog, J. (author)
- Univ Gothenburg, Dept Psychol, Ctr Hlth & Ageing AGECAP, Gothenburg, Sweden
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- Sjoberg, L. (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Stockholm Univ, Aging Res Ctr, Stockholm, Sweden
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- Wang, Hui-Xin (author)
- Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Stressforskningsinstitutet,Stockholm Univ, Aging Res Ctr, Stockholm, Sweden
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- Fratiglioni, L. (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Stockholm Gerontology Research Center, Sweden,Stockholm Univ, Aging Res Ctr, Stockholm, Sweden
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- Skoog, I. (author)
- Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Ctr Hlth & Ageing AGECAP, Gothenburg, Sweden
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- Kivipelto, M. (author)
- Karolinska Institutet
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(creator_code:org_t)
- 2021-07-13
- 2021
- English.
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In: Alzheimers & Dementia. - : Wiley. - 1552-5260 .- 1552-5279. ; 17:7, s. 1166-1178
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Abstract
Subject headings
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- Introduction Evidence on sex differences in the risk for dementia has been mixed. The goal was to assess sex differences in the development of dementia, and in the effects of a lifestyle intervention. Methods Two strategies were adopted, one using combined data from three large Nordic population-based cohort studies (n = 2289), adopting dementia as outcome, and 2-year multidomain lifestyle intervention (n = 1260), adopting cognitive change as outcome. Results There was higher risk for dementia after age 80 years in women. The positive effects of the lifestyle intervention on cognition did not significantly differ between men and women. Sex-specific analyses suggested that different vascular, lifestyle, and psychosocial risk factors are important for women and men in mid- and late-life. Conclusion Women had higher risk for dementia among the oldest individuals. Lifestyle interventions may be effectively implemented among older men and women.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
Keyword
- cohort study
- dementia
- lifestyle intervention
- risk factors
- sex differences
- cohort study
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Sindi, S.
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Kåreholt, Ingema ...
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Ngandu, T.
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Rosenberg, A.
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Kulmala, J.
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Johansson, Lena, ...
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show more...
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Wetterberg, Hann ...
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Skoog, J.
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Sjoberg, L.
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Wang, Hui-Xin
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Fratiglioni, L.
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Skoog, I.
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Kivipelto, M.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Geriatrics
- Articles in the publication
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Alzheimers & Dem ...
- By the university
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University of Gothenburg
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Stockholm University
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Jönköping University
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Karolinska Institutet