Clinical and MRI findings in lumbar spinal stenosis: baseline data from the NORDSTEN study

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Clinical and MRI findings in lumbar spinal stenosis: baseline data from the NORDSTEN study

Aaen, J. (author)

Austevoll, I. M. (author)

Hellum, C. (author)

Storheim, K. (author)

Myklebust, T. A. (author)

Banitalebi, H. (author)

Anvar, M. (author)

Brox, J. I. (author)

Weber, C. (author)

Solberg, T. (author)

Grundnes, O. (author)

Brisby, Helena, 1965 (author): Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för ortopedi,Institute of Clinical Sciences, Department of Orthopaedics

Indrekvam, K. (author)

Hermansen, E. (author)

Article; Early, Access (author)

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(creator_code:org_t)

2021-11-19
2022
English.
In: European Spine Journal. - : Springer Science and Business Media LLC. - 0940-6719 .- 1432-0932. ; 31:6, s. 1391-1398

Related links:: https://link.springe...; show more...; https://gup.ub.gu.se...; https://doi.org/10.1...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

Purpose The aim was to describe magnetic resonance imaging findings in patients planned for lumbar spinal stenosis surgery. Further, to describe possible associations between MRI findings and patient characteristics with patient reported disability or pain. Methods The NORDSTEN spinal stenosis trial included 437 patients planned for surgical decompression of LSS. The following MRI findings were evaluated before surgery: morphological (Schizas) and quantitative (cross-sectional area) grade of stenosis, disk degeneration (Pfirrmann), facet joint tropism and fatty infiltration of the multifidus muscle. Patients were dichotomized into a moderate or severe category for each radiological parameter classification. A multivariable linear regression analysis was performed to investigate the association between MRI findings and preoperative scores for Oswestry Disability Index, Zurich Claudication Questionnaire and Numeric rating scale for back and leg pain. The following patient characteristics were included in the analysis: gender, age, smoking and weight. Results The percentage of patients with severe scores was as follows: Schizas (C + D) 71.3%, cross-sectional area (< 75 mm(2)) 86.8%, Pfirrmann (4 + 5) 58.1%, tropism (>= 15 degrees) 11.9%, degeneration of multifidus muscle (2-4) 83.7%. Regression coefficients indicated minimal changes in severity of symptoms when comparing the groups with moderate and severe MRI findings. Only gender had a significant and clinically relevant association with ODI score. Conclusion In this cross-sectional study, the majority of the patients had MRI findings classified as severe LSS changes, but the findings had no clinically relevant association with patient reported disability and pain at baseline. Patient characteristics have a larger impact on disability and pain than radiological findings.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Ortopedi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Orthopaedics (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)

Keyword

Lumbar spinal stenosis
Schizas
DSCA
Pfirrmann
Tropism
cross-sectional area
cauda-equina
dural sac
disability
diagnosis
surgery
pain
degeneration
association
severity
Neurosciences & Neurology
Orthopedics

Publication and Content Type

ref (subject category)
art (subject category)

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By the author/editor: Aaen, J.; Austevoll, I. M.; Hellum, C.; Storheim, K.; Myklebust, T. A.; Banitalebi, H.; show more...; Anvar, M.; Brox, J. I.; Weber, C.; Solberg, T.; Grundnes, O.; Brisby, Helena, ...; Indrekvam, K.; Hermansen, E.; Article; Early, ...; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Orthopaedics

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By the university: University of Gothenburg

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